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Psma4 Gene Detail
Summary
  • Symbol
    Psma4
  • Name
    proteasome subunit alpha 4
  • Synonyms
    C9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347060
    NCBI Gene: 26441
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr9:54858074-54865314 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.84 cM, cytoband C
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    384 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347060
 protein coding gene Chr9:54858074-54865316 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034834
 protein coding gene Chr9:54019573-54026807 (+)
A/J MGP_AJ_G0034815
 protein coding gene Chr9:52289908-52297148 (+)
AKR/J MGP_AKRJ_G0034744
 protein coding gene Chr9:53481090-53488330 (+)
BALB/cJ MGP_BALBcJ_G0034807
 protein coding gene Chr9:52069456-52077227 (+)
C3H/HeJ MGP_C3HHeJ_G0034517
 protein coding gene Chr9:53947371-53954611 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035326
 protein coding gene Chr9:55523243-55530483 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032238
 protein coding gene Chr9:51705499-51712536 (+)
CAST/EiJ MGP_CASTEiJ_G0033839
 protein coding gene Chr9:53964457-53973704 (+)
CBA/J MGP_CBAJ_G0034488
 protein coding gene Chr9:57459580-57473396 (+)
DBA/2J MGP_DBA2J_G0034647
 protein coding gene Chr9:52184061-52191295 (+)
FVB/NJ MGP_FVBNJ_G0034589
 protein coding gene Chr9:51387085-51394310 (+)
LP/J MGP_LPJ_G0034730
 protein coding gene Chr9:54330910-54338271 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034632
 protein coding gene Chr9:58982294-58989703 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035348
 protein coding gene Chr9:53503333-53510573 (+)
PWK/PhJ MGP_PWKPhJ_G0033543
 protein coding gene Chr9:52163127-52169293 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033378
 protein coding gene Chr9:53759958-53766886 (+)
WSB/EiJ MGP_WSBEiJ_G0033951
 protein coding gene Chr9:53462755-53471286 (+)



Homology
more
  • Human Ortholog
    PSMA4, proteasome 20S subunit alpha 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMA4, proteasome 20S subunit alpha 4
  • Synonyms
    HC9, HsT17706, PSC9
  • Links
    NCBI Gene ID: 5685
    UniProt: P25789

  • Chr Location
    15q25.1; chr15:78540405-78552417 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    1
  • cDNA Data
    177
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032301 Ensembl Gene Model | MGI Sequence Detail 7241 C57BL/6J ±  kb
transcript ENSMUST00000034848 Ensembl | MGI Sequence Detail 1165 Not Applicable  
polypeptide ENSMUSP00000034848 Ensembl | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 177
    cDNA 177

    Microarray probesets 3
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 11
    Phenotypes 4
  • Earliest
    J:57232 Elenich LA, et al., The complete primary structure of mouse 20S proteasomes. Immunogenetics. 1999 Sep;49(10):835-42
  • Latest
    J:354587 Nedomova M, et al., DDI2 protease controls embryonic development and inflammation via TCF11/NRF1. iScience. 2024 Oct 18;27(10):110893
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory