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Decr2 Gene Detail
Summary
  • Symbol
    Decr2
  • Name
    2-4-dienoyl-Coenzyme A reductase 2, peroxisomal
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347059
    NCBI Gene: 26378
  • Gene Overview
    MyGene.info: DECR2
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26081211-26090164 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 13.06 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    142 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347059
protein coding gene Chr17:26081211-26090329 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023388
protein coding gene Chr17:25209348-25219674 (-)
A/J MGP_AJ_G0023347
protein coding gene Chr17:24468521-24477655 (-)
AKR/J MGP_AKRJ_G0023313
protein coding gene Chr17:24575543-24586137 (-)
BALB/cJ MGP_BALBcJ_G0023352
protein coding gene Chr17:24690243-24700147 (-)
C3H/HeJ MGP_C3HHeJ_G0023112
protein coding gene Chr17:24966445-24975968 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023794
protein coding gene Chr17:26275367-26284769 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021270
protein coding gene Chr17:21919595-21929720 (-)
CAST/EiJ MGP_CASTEiJ_G0022614
protein coding gene Chr17:24860761-24871919 (-)
CBA/J MGP_CBAJ_G0023087
protein coding gene Chr17:27203537-27214269 (-)
DBA/2J MGP_DBA2J_G0023217
protein coding gene Chr17:24062972-24072149 (-)
FVB/NJ MGP_FVBNJ_G0023187
protein coding gene Chr17:23819866-23829611 (-)
LP/J MGP_LPJ_G0023294
protein coding gene Chr17:25496372-25508220 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023206
protein coding gene Chr17:26772992-26784961 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023834
protein coding gene Chr17:24907080-24918365 (-)
PWK/PhJ MGP_PWKPhJ_G0022363
protein coding gene Chr17:22832898-22841915 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022181
protein coding gene Chr17:22984160-22996779 (-)
WSB/EiJ MGP_WSBEiJ_G0022677
protein coding gene Chr17:24948550-24958326 (-)



Homology
more
  • Human Ortholog
    DECR2, 2,4-dienoyl-CoA reductase 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    DECR2, 2,4-dienoyl-CoA reductase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PDCR, SDR17C1
  • Links
    NCBI Gene ID: 26063
    neXtProt AC: NX_Q9NUI1
    UniProt: Q9NUI1

  • Chr Location
    16p13.3; chr16:401858-412487 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 26378 NCBI Gene Model | MGI Sequence Detail 8954 C57BL/6J ±  kb
transcript NM_011933 RefSeq | MGI Sequence Detail 2051 C57BL/6  
polypeptide Q9WV68 UniProt | EBI | MGI Sequence Detail 292 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    cDNA 48
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:57230 Geisbrecht BV, et al., The mouse gene PDCR encodes a peroxisomal delta(2), delta(4)-dienoyl-CoA reductase. J Biol Chem. 1999 Sep 3;274(36):25814-20
  • Latest
    J:194116 Flachs P, et al., Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility. PLoS Genet. 2012;8(11):e1003044

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory