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Decr2 Gene Detail
Summary
  • Symbol
    Decr2
  • Name
    2-4-dienoyl-Coenzyme A reductase 2, peroxisomal
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347059
    NCBI Gene: 26378
  • Gene Overview
    MyGene.info: DECR2
Location & Maps
more
  • Sequence Map
    Chr17:26081211-26090329 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9119 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 13.06 cM, cytoband B1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DECR2, 2,4-dienoyl-CoA reductase 2, peroxisomal
  • Vertebrate Orthologs
    8
  • Human Ortholog
    DECR2, 2,4-dienoyl-CoA reductase 2, peroxisomal
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PDCR, SDR17C1
  • Links
    NCBI Gene ID: 26063
    neXtProt AC: NX_Q9NUI1

  • Chr Location
    16p13.3; chr16:401858-412487 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    6
  • Radiation induced
    2
  • Targeted
    4
  • Genomic Mutations
    2 involving Decr2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021323 VEGA Gene Model | MGI Sequence Detail 9119 C57BL/6J ±  kb
transcript OTTMUST00000050550 VEGA | MGI Sequence Detail 2187 Not Applicable  
polypeptide OTTMUSP00000023614 VEGA | MGI Sequence Detail 292 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    142 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000006374 peroxisomal 2,4-dienoyl-CoA reductase
  • EC
  • InterPro Domains
    IPR016040 NAD(P)-binding domain
    IPR002347 Short-chain dehydrogenase/reductase SDR
Molecular
Reagents
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  • All nucleic 48
    cDNA 47
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:57230 Geisbrecht BV, et al., The mouse gene PDCR encodes a peroxisomal delta(2), delta(4)-dienoyl-CoA reductase. J Biol Chem. 1999 Sep 3;274(36):25814-20
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory