Aldh1a7
Gene Detail

Symbol Name ID

Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 MGI:1347050

Synonyms

Ahd2-like, Aldh-pb

Feature Type

protein coding gene

Genetic Map

Chromosome 19

13.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr19:20692953-20727562 bp, - strand From VEGA annotation of GRCm38   34610 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:122182  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: NAD-dependent aldehyde dehydrogenase
Gene Tree: Aldh1a7

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	metabolic process, protein homotetramerization
Component	cytoplasm
Function	3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (4)    Tissues (2)   
Theiler Stages: 18, 26

Assay Type	Results
RT-PCR	4

cDNA source data(32)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(34) cDNA(32) Primer pair(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000028314 (Evidence)
Ensembl Gene Model	ENSMUSG00000024747 (Evidence)
Entrez Gene	26358 (Evidence)
UniGene	14609
DFCI	TC1582542
DoTS	DT.87079446
NIA Mouse Gene Index	U038905
EC	1.2.1.3
Consensus CDS Project	CCDS29696.1
International Mouse Knockout Project Status	Aldh1a7

Sequences

Length	Strain/Species
genomic	OTTMUSG00000028314	VEGA Gene Model | MGI Sequence Detail	34610	C57BL/6J
transcript	OTTMUST00000070176	VEGA | MGI Sequence Detail	2066	Not Applicable
polypeptide	OTTMUSP00000035734	VEGA | MGI Sequence Detail	501	Not Applicable

All sequences(20) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(18 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR016160	Aldehyde dehydrogenase, conserved site
InterPro	IPR016163	Aldehyde dehydrogenase, C-terminal
InterPro	IPR015590	Aldehyde dehydrogenase domain
InterPro	IPR016162	Aldehyde dehydrogenase, N-terminal
InterPro	IPR016161	Aldehyde/histidinol dehydrogenase
Protein Ontology	PR:000004564	aldehyde dehydrogenase, cytosolic 1

References

(Earliest) J:54527 Hsu LC, et al., Molecular analysis of two closely related mouse aldehyde dehydrogenase genes: identification of a role for Aldh1, but not Aldh-pb, in the biosynthesis of retinoic acid. Biochem J. 1999 Apr 15;339(Pt 2):387-95
(Latest) J:188607 Lee LM, et al., A paradoxical teratogenic mechanism for retinoic acid. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13668-73
All references(36)

Other accession IDs

MGI:2147624