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Sema4g
Gene Detail
Symbol

Name
ID
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
MGI:1347047
Feature Type
protein coding gene
Genetic Map
Chromosome 19
38.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr19:44989101-45003397 bp, + strand
From VEGA annotation of GRCm38

  14297 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22682  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: SEMA4G
Protein SuperFamily: semaphorin
Gene Tree: Sema4g

Human
homologs
SEMA4G, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 57715
neXtProt AC: NX_Q9NTN9

Human Chr (Location): 10q24.31; chr10:100969482-100985616 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(6) Targeted(6)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a targeted allele exhibit normal cerebellar morphology.
 
Interactions
Sema4g interacts with 323 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process cell differentiation, multicellular organismal development, ...
Component integral component of membrane, membrane, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (313)    Tissues (103)    Images (43)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 304
Northern blot 9
cDNA source data(73)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase sema4g    NEW 
Molecular
reagents
All nucleic(74) cDNA(74)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000014898 (Evidence)
Ensembl Gene Model ENSMUSG00000025207 (Evidence)
Entrez Gene 26456 (Evidence)
UniGene 34404
DFCI TC1603019, TC1601644, TC1579617
DoTS DT.94337269, DT.101336834, DT.527985
NIA Mouse Gene Index U019495
Consensus CDS Project CCDS29853.1
International Mouse Phenotyping Consortium Status Sema4g
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014898 VEGA Gene Model | MGI Sequence Detail 14297 C57BL/6J ±  kb
transcript OTTMUST00000035392 VEGA | MGI Sequence Detail 4548 Not Applicable 
polypeptide OTTMUSP00000015815 VEGA | MGI Sequence Detail 837 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(66 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR002165 Plexin
InterPro IPR016201 Plexin-like fold
InterPro IPR027231 Semaphorin
InterPro IPR001627 Semaphorin/CD100 antigen
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000014626 semaphorin-4G
References
(Earliest) J:57796 Li H, et al., Characterization and expression of sema4g, a novel member of the semaphorin gene family. Mech Dev. 1999 Sep;87(1-2):169-73
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(44)
Other
accession IDs
MGI:2147576, MGI:2147747

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory