Sema4g
Gene Detail

Symbol Name ID

Sema4g sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G MGI:1347047

Feature Type

protein coding gene

Genetic Map

Chromosome 19

38.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr19:44989101-45003397 bp, + strand From VEGA annotation of GRCm38   14297 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:22682  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Protein SuperFamily: semaphorin
Gene Tree: Sema4g

Human homologs

Human Homolog		SEMA4G, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
NCBI Gene ID		57715
neXtProt AC		NX_Q9NTN9
Human Chr (Location)		10q24.31; chr10:102732286-102745373 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(12) : Targeted(6) Gene trapped(6)
 

Mice homozygous for a targeted allele exhibit normal cerebellar morphology.

 

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	cell differentiation, multicellular organismal development, ...
Component	integral to membrane, membrane, ...
Function	receptor activity

External Resources: FuncBase

Expression

Literature Summary: (11 records)
Data Summary: Results (313)    Tissues (102)    Images (43)
Theiler Stages: 13, 14, 15, 17, 20, 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	304
Northern blot	9

cDNA source data(73)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(74) cDNA(74)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000014898 (Evidence)
Ensembl Gene Model	ENSMUSG00000025207 (Evidence)
Entrez Gene	26456 (Evidence)
UniGene	34404
DFCI	TC1579617, TC1601644, TC1603019
DoTS	DT.101336834, DT.527985, DT.94337269
NIA Mouse Gene Index	U019495
Consensus CDS Project	CCDS29853.1
International Mouse Knockout Project Status	Sema4g

Sequences

Length	Strain/Species
genomic	OTTMUSG00000014898	VEGA Gene Model | MGI Sequence Detail	14297	C57BL/6J
transcript	OTTMUST00000035392	VEGA | MGI Sequence Detail	4548	Not Applicable
polypeptide	OTTMUSP00000015815	VEGA | MGI Sequence Detail	837	Not Applicable

All sequences(33) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(53 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007110	Immunoglobulin-like domain
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003599	Immunoglobulin subtype
InterPro	IPR002165	Plexin
InterPro	IPR016201	Plexin-like fold
InterPro	IPR003659	Plexin/semaphorin/integrin
InterPro	IPR027231	Semaphorin
InterPro	IPR001627	Semaphorin/CD100 antigen
InterPro	IPR015943	WD40/YVTN repeat-like-containing domain
Protein Ontology	PR:000014626	semaphorin-4G

References

(Earliest) J:57796 Li H, et al., Characterization and expression of sema4g, a novel member of the semaphorin gene family. Mech Dev. 1999 Sep;87(1-2):169-73
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(42)

Other accession IDs

MGI:2147576, MGI:2147747