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Psmb2 Gene Detail
Summary
  • Symbol
    Psmb2
  • Name
    proteasome (prosome, macropain) subunit, beta type 2
  • Synonyms
    D4Wsu33e, HC7-I
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347045
    NCBI Gene: 26445
  • Gene Overview
    MyGene.info: PSMB2
Location & Maps
more
  • Sequence Map
    Chr4:126677630-126709714 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      32085 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 60.90 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PSMB2, proteasome subunit beta 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PSMB2, proteasome subunit beta 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HC7-I
  • Links
    NCBI Gene ID: 5690
    neXtProt AC: NX_P49721

  • Chr Location
    1p34.2; chr1:35599541-35641844 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    2
  • Gene trapped
    6
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Psmb2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009281 VEGA Gene Model | MGI Sequence Detail 32085 C57BL/6J ±  kb
transcript OTTMUST00000021044 VEGA | MGI Sequence Detail 859 Not Applicable  
polypeptide OTTMUSP00000009645 VEGA | MGI Sequence Detail 201 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    159 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-34196, MGI:106502, MGI:2140499, MGI:2140555
References
more
  • Summaries
    All 35
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory