Plod2
Gene Detail

Symbol Name ID

Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 MGI:1347007

Synonyms

D530025C14Rik, LH2, lysyl hydroxylase 2, Plod-2

Feature Type

protein coding gene

Genetic Map

Chromosome 9

48.40 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr9:92542223-92608428 bp, + strand From VEGA annotation of GRCm38   66206 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:22681  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: procollagen-lysine 5-dioxygenase
Gene Tree: Plod2

Human homologs

Human Homolog		PLOD2, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
NCBI Gene ID		5352
neXtProt AC		NX_O00469
Human Synonyms		LH2, TLH
Human Chr (Location)		3q24; chr3:145787227-145879282 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human PLOD2

Alleles and phenotypes

All alleles(5) : Gene trapped(5)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	oxidation-reduction process
Component	endoplasmic reticulum, membrane
Function	iron ion binding, L-ascorbic acid binding, ...

External Resources: FuncBase

Expression

Literature Summary: (9 records)
Data Summary: Results (192)    Tissues (122)    Images (34)
Theiler Stages: 10, 18, 21, 22, 23, 25, 28

Assay Type	Results
RNA in situ	178
RT-PCR	14

cDNA source data(79)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(84) cDNA(82) Primer pair(2)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000031153 (Evidence)
Ensembl Gene Model	ENSMUSG00000032374 (Evidence)
Entrez Gene	26432 (Evidence)
UniGene	79983
DFCI	TC1576014, TC1696479
DoTS	DT.87068890, DT.94175439
EC	1.14.11.4
Consensus CDS Project	CCDS23408.1, CCDS52887.1
International Mouse Knockout Project Status	Plod2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031153	VEGA Gene Model | MGI Sequence Detail	66206	C57BL/6J
transcript	OTTMUST00000077171	VEGA | MGI Sequence Detail	3663	Not Applicable
polypeptide	OTTMUSP00000040752	VEGA | MGI Sequence Detail	758	Not Applicable

All sequences(43) RefSeq(4) UniProt(3)

Polymorphisms

PCR(1) : SNPs(393 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR005123	Oxoglutarate/iron-dependent dioxygenase
InterPro	IPR001006	Procollagen-lysine 5-dioxygenase
InterPro	IPR006620	Prolyl 4-hydroxylase, alpha subunit
Protein Ontology	PR:000012877	procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

References

(Earliest) J:56595 Ruotsalainen H, et al., Characterization of cDNAs for mouse lysyl hydroxylase 1, 2 and 3, their phylogenetic analysis and tissue-specific expression in the mouse. Matrix Biol. 1999 Jun;18(3):325-9
(Latest) J:189252 Tao G, et al., Collagen XIV is important for growth and structural integrity of the myocardium. J Mol Cell Cardiol. 2012 Nov;53(5):626-38
All references(40)

Other accession IDs

MGI:1925825