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Plod2
Gene Detail
Symbol

Name
ID
Plod2
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
MGI:1347007
Synonyms
D530025C14Rik, LH2, lysyl hydroxylase 2, Plod-2
Feature Type
protein coding gene
Genetic Map
Chromosome 9
48.40 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:92542223-92608428 bp, + strand
From VEGA annotation of GRCm38

  66206 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22681  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: procollagen-lysine 5-dioxygenase
Gene Tree: Plod2

Human
homologs
Human Homolog   PLOD2, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
NCBI Gene ID 5352
neXtProt AC  NX_O00469
Human Synonyms  BRKS2, LH2, TLH
Human Chr (Location)  3q24; chr3:146069436-146161495 (-)  GRCh38.p2
Disease Associations  (1) Diseases Associated with Human PLOD2
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Plod2 interacts with 191 markers (Mir7-2, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (10 records)
Data Summary: Results (192)    Tissues (122)    Images (34)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 178
RT-PCR 14
cDNA source data(77)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(82) cDNA(80) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000031153 (Evidence)
Ensembl Gene ModelENSMUSG00000032374 (Evidence)
Entrez Gene26432 (Evidence)
UniGene79983
DFCITC1696479, TC1576014
DoTSDT.94175439, DT.87068890
EC1.14.11.4
Consensus CDS ProjectCCDS23408.1, CCDS52887.1
International Mouse Knockout Project StatusPlod2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031153 VEGA Gene Model | MGI Sequence Detail 66206 C57BL/6J ±  kb
transcript OTTMUST00000077171 VEGA | MGI Sequence Detail 3663 Not Applicable 
polypeptide OTTMUSP00000040752 VEGA | MGI Sequence Detail 758 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(4) UniProt(3)
Polymorphisms
PCR(1) : SNPs within 2kb(907 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005123 Oxoglutarate/iron-dependent dioxygenase
InterPro IPR001006 Procollagen-lysine 5-dioxygenase
InterPro IPR006620 Prolyl 4-hydroxylase, alpha subunit
Protein Ontology PR:000012877 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
References
(Earliest) J:56595 Ruotsalainen H, et al., Characterization of cDNAs for mouse lysyl hydroxylase 1, 2 and 3, their phylogenetic analysis and tissue-specific expression in the mouse. Matrix Biol. 1999 Jun;18(3):325-9
(Latest) J:214961 Milgrom-Hoffman M, et al., Endothelial cells regulate neural crest and second heart field morphogenesis. Biol Open. 2014;3(8):679-88
All references(42)
Other
accession IDs
MGI:1925825

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/21/2015
MGI 5.21
The Jackson Laboratory