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Ciao1 Gene Detail
Summary
  • Symbol
    Ciao1
  • Name
    cytosolic iron-sulfur protein assembly 1
  • Synonyms
    Wdr39
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346998
    NCBI Gene: 26371
  • Gene Overview
    MyGene.info: CIAO1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:127240938-127247816 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 61.86 cM, cytoband F3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    116 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1346998
protein coding gene Chr2:127240938-127247816 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026453
protein coding gene Chr2:130517698-130524866 (-)
A/J MGP_AJ_G0026417
protein coding gene Chr2:125224355-125231523 (-)
AKR/J MGP_AKRJ_G0026392
protein coding gene Chr2:128799441-128806610 (-)
BALB/cJ MGP_BALBcJ_G0026429
protein coding gene Chr2:125493514-125500679 (-)
C3H/HeJ MGP_C3HHeJ_G0026172
protein coding gene Chr2:129320791-129327652 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026874
protein coding gene Chr2:134613349-134620510 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024251
protein coding gene Chr2:120070329-120075898 (-)
CAST/EiJ MGP_CASTEiJ_G0025633
protein coding gene Chr2:129527784-129534968 (-)
CBA/J MGP_CBAJ_G0026152
protein coding gene Chr2:139603231-139610092 (-)
DBA/2J MGP_DBA2J_G0026286
protein coding gene Chr2:124636225-124643086 (-)
FVB/NJ MGP_FVBNJ_G0026250
protein coding gene Chr2:123280926-123287817 (-)
LP/J MGP_LPJ_G0026391
protein coding gene Chr2:130750973-130758141 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026270
protein coding gene Chr2:143634378-143641546 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026929
protein coding gene Chr2:128831141-128838032 (-)
PWK/PhJ MGP_PWKPhJ_G0025369
protein coding gene Chr2:124180442-124187303 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025171
protein coding gene Chr2:127904216-127911569 (-)
WSB/EiJ MGP_WSBEiJ_G0025707
protein coding gene Chr2:129723917-129731091 (-)



Homology
more
  • Human Ortholog
    CIAO1, cytosolic iron-sulfur assembly component 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CIAO1, cytosolic iron-sulfur assembly component 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CIA1, WDR39
  • Links
    NCBI Gene ID: 9391
    neXtProt AC: NX_O76071
    UniProt: O76071

  • Chr Location
    2q11.2; chr2:96266146-96274179 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 55850
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CIAO1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Ciao1
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 26371 NCBI Gene Model | MGI Sequence Detail 6879 C57BL/6J ±  kb
transcript NM_025296 RefSeq | MGI Sequence Detail 3075 C57BL/6  
polypeptide Q99KN2 UniProt | EBI | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 6
Other
Accession IDs
less
MGI:2139326
References
more
  • Summaries
    All 44
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory