Igbp1
Gene Detail

Symbol Name ID

Igbp1 immunoglobulin (CD79A) binding protein 1 MGI:1346500

Synonyms

alpha 4, p52, Pc52, Tap42

Feature Type

protein coding gene

Genetic Map

Chromosome X

43.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

ChrX:100494291-100516125 bp, + strand From VEGA annotation of GRCm38   21835 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:44067  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 2 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Igbp1

Human homologs

Human Homolog		IGBP1, immunoglobulin (CD79A) binding protein 1
NCBI Gene ID		3476
neXtProt AC		NX_P78318
Human Synonyms		ALPHA-4, IBP1
Human Chr (Location)		Xq13.1-q13.3; chrX:69353318-69386174 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human IGBP1

Alleles and phenotypes

All alleles(4) : Targeted(3) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	B cell activation, negative regulation of apoptotic process, ...
Component	cytoplasm
Function	mitogen-activated protein kinase kinase binding, protein binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (14)    Tissues (14)    Images (3)
Theiler Stages: 17, 18, 23

Assay Type	Results
RNA in situ	14

cDNA source data(19)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(25) Genomic(2) cDNA(22) Primer pair(1)
Microarray probesets(8)

Other database links

VEGA Gene Model	OTTMUSG00000018243 (Evidence)
Ensembl Gene Model	ENSMUSG00000031221 (Evidence)
Entrez Gene	18518 (Evidence)
DFCI	TC1574073, TC1607874, TC1656531
DoTS	DT.536616, DT.91379982
PDB	3QC1
Consensus CDS Project	CCDS30302.1
International Mouse Knockout Project Status	Igbp1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000018243	VEGA Gene Model | MGI Sequence Detail	21835	C57BL/6J
transcript	OTTMUST00000044098	VEGA | MGI Sequence Detail	1518	Not Applicable
polypeptide	OTTMUSP00000019822	VEGA | MGI Sequence Detail	340	Not Applicable

All sequences(51) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(84 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007304	TAP42-like protein
Protein Ontology	PR:000008941	immunoglobulin-binding protein 1

References

(Earliest) J:27712 Kuwahara K, et al., Identification of a 52-kDa molecule (p52) coprecipitated with the Ig receptor-related MB-1 protein that is inducibly phosphorylated by the stimulation with phorbol myristate acetate. J Immunol. 1994 Mar 15;152(6):2742-52
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(47)

Other accession IDs

MGD-MRK-32087, MGI:105048, MGI:2147845, MGI:2147906, MGI:2148003, MGI:2148070