|Human Homolog||NR0B2, nuclear receptor subfamily 0, group B, member 2|
|NCBI Gene ID||8431|
|Human Synonyms||SHP, SHP1|
|Human Chr (Location)||1p36.1; chr1:26911484-26914076 (-) GRCh38.p2|
|Disease Associations||(1) Diseases Associated with Human NR0B2|
Mice homozygous for a targeted null mutation are viable and fertile and exhibit no major defects in cholesterol metabolism under normal conditions. Under high cholesterol and cholic acid or iodine-deficient diets, mice exhibit decreased lipid levels.
|Process||negative regulation of gene expression, negative regulation of sequence-specific DNA binding transcription factor activity, ...|
|Component||cytoplasm, nucleus, ...|
|Function||DNA binding, peroxisome proliferator activated receptor binding, ...|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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