Mice homozygous for a targeted null mutation are viable and fertile and exhibit no major defects in cholesterol metabolism under normal conditions. Under high cholesterol and cholic acid or iodine-deficient diets, mice exhibit decreased lipid levels.
|Process||negative regulation of gene expression, negative regulation of sequence-specific DNA binding transcription factor activity, ...|
|Component||cytoplasm, nucleus, ...|
|Function||DNA binding, peroxisome proliferator activated receptor binding, ...|
|VEGA Gene Model||OTTMUSG00000011155 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000037583 (Evidence)|
|Entrez Gene||23957 (Evidence)|
|NIA Mouse Gene Index||U004919|
|Consensus CDS Project||CCDS18751.1|
|International Mouse Phenotyping Consortium Status||Nr0b2|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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