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Tekt2
Gene Detail
Symbol

Name
ID
Tekt2
tektin 2
MGI:1346335
Synonyms
tektin-t
Feature Type
protein coding gene
Genetic Map
Chromosome 4
60.37 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:126322121-126325688 bp, - strand
From VEGA annotation of GRCm38

  3568 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8043  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Tekt2

Human
homologs
Human Homolog TEKT2, tektin 2 (testicular)
NCBI Gene ID 27285
neXtProt AC  NX_Q9UIF3
Human Synonyms  h-tektin-t, TEKTB1, TEKTIN-T
Human Chr (Location)  1p34.3; chr1:36084075-36088276 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trapped allele exhibit male infertility and impaired motility of both sperm flagella and tracheal cilia due to altered dynein inner arm morphology and function.
 
Interactions
Tekt2 interacts with 15 markers (Mir15a, Mir136, Mir146, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell projection organization, inner dynein arm assembly, ...
Component cell projection, cilium, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (7)    Tissues (7)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
RT-PCR 6
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000009354 (Evidence)
Ensembl Gene ModelENSMUSG00000028845 (Evidence)
Entrez Gene24084 (Evidence)
DFCITC1583617
DoTSDT.526107, DT.94231527
NIA Mouse Gene IndexU025519
Consensus CDS ProjectCCDS18651.1
International Mouse Knockout Project StatusTekt2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009354 VEGA Gene Model | MGI Sequence Detail 3568 C57BL/6J ±  kb
transcript OTTMUST00000021319 VEGA | MGI Sequence Detail 1542 Not Applicable 
polypeptide OTTMUSP00000009749 VEGA | MGI Sequence Detail 430 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(31 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000435 Tektin
Protein Ontology PR:000016227 tektin-2
References
(Earliest) J:56926 Iguchi N, et al., Molecular cloning of haploid germ cell-specific tektin cDNA and analysis of the protein in mouse testis. FEBS Lett. 1999 Aug 6;456(2):315-21
(Latest) J:182741 Alten L, et al., Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1. Development. 2012 Apr;139(7):1276-84
All references(37)
Other
accession IDs
MGI:2140423

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory