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Tekt2 Gene Detail
Summary
  • Symbol
    Tekt2
  • Name
    tektin 2
  • Synonyms
    tektin-t
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346335
    NCBI Gene: 24084
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:126322121-126325688 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 60.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    31 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1346335
protein coding gene Chr4:126322116-126325841 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028779
protein coding gene Chr4:127996772-128000338 (-)
A/J MGP_AJ_G0028738
protein coding gene Chr4:122959147-122962713 (-)
AKR/J MGP_AKRJ_G0028691
protein coding gene Chr4:126338274-126341841 (-)
BALB/cJ MGP_BALBcJ_G0028761
protein coding gene Chr4:123534813-123538380 (-)
C3H/HeJ MGP_C3HHeJ_G0028475
protein coding gene Chr4:126405208-126408775 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029203
protein coding gene Chr4:132888143-132891710 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026476
protein coding gene Chr4:116106282-116109767 (-)
CAST/EiJ MGP_CASTEiJ_G0027908
protein coding gene Chr4:124512083-124515620 (-)
CBA/J MGP_CBAJ_G0028441
protein coding gene Chr4:136088935-136092502 (-)
DBA/2J MGP_DBA2J_G0028590
protein coding gene Chr4:123413249-123416816 (-)
FVB/NJ MGP_FVBNJ_G0028557
protein coding gene Chr4:122069340-122072883 (-)
LP/J MGP_LPJ_G0028691
protein coding gene Chr4:128283264-128286830 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028583
protein coding gene Chr4:141122815-141126358 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029241
protein coding gene Chr4:126692365-126695915 (-)
PWK/PhJ MGP_PWKPhJ_G0027629
protein coding gene Chr4:119901214-119904767 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027455
protein coding gene Chr4:122519507-122523038 (-)
WSB/EiJ MGP_WSBEiJ_G0027988
protein coding gene Chr4:126793621-126797188 (-)



Homology
more
  • Human Ortholog
    TEKT2, tektin 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TEKT2, tektin 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    h-tektin-t, TEKTB1, TEKTIN-T
  • Links
    NCBI Gene ID: 27285
    neXtProt AC: NX_Q9UIF3
    UniProt: Q9UIF3

  • Chr Location
    1p34.3; chr1:36084075-36088275 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8043
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TEKT2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele exhibit male infertility and impaired motility of both sperm flagella and tracheal cilia due to altered dynein inner arm morphology and function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028845 Ensembl Gene Model | MGI Sequence Detail 3568 C57BL/6J ±  kb
    transcript ENSMUST00000102616 Ensembl | MGI Sequence Detail 1542 Not Applicable  
    polypeptide ENSMUSP00000099676 Ensembl | MGI Sequence Detail 430 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 6
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2140423
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:56926 Iguchi N, et al., Molecular cloning of haploid germ cell-specific tektin cDNA and analysis of the protein in mouse testis. FEBS Lett. 1999 Aug 6;456(2):315-21
    • Latest
      J:241053 Yamaguchi A, et al., Molecular cloning and subcellular localization of Tektin2-binding protein 1 (Ccdc 172) in rat spermatozoa. J Histochem Cytochem. 2014 Apr;62(4):286-97

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    03/13/2019
    MGI 6.13
    The Jackson Laboratory