About   Help   FAQ
Gpr34
Gene Detail
Symbol

Name
ID
Gpr34
G protein-coupled receptor 34
MGI:1346334
Feature Type
protein coding gene
Genetic Map
Chromosome X
8.55 cM, cytoband A1.3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:13632089-13640856 bp, + strand
From VEGA annotation of GRCm38

  8768 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36174  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: probable G protein-coupled receptor 34
Gene Tree: Gpr34

Human
homologs
Human Homolog GPR34, G protein-coupled receptor 34
NCBI Gene ID 2857
neXtProt AC  NX_Q9UPC5
Human Synonyms  LYPSR1
Human Chr (Location)  Xp11.4; chrX:41688968-41697277 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele exhibit increased monocyte migration and susceptibility to type IV hypersensitivity and fungal infection.
 
Interactions
Gpr34 interacts with 120 markers (Mir1b, Mir17, Mir19a, ...)
Expression
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(13) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000016906 (Evidence)
Ensembl Gene ModelENSMUSG00000040229 (Evidence)
Entrez Gene23890 (Evidence)
UniGene487326
DFCITC1598763, TC1582815
DoTSDT.111033009, DT.55128522
NIA Mouse Gene IndexU019726
Consensus CDS ProjectCCDS30028.1
International Mouse Knockout Project StatusGpr34
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016906 VEGA Gene Model | MGI Sequence Detail 8768 C57BL/6J ±  kb
transcript OTTMUST00000041027 VEGA | MGI Sequence Detail 2088 Not Applicable 
polypeptide OTTMUSP00000018373 VEGA | MGI Sequence Detail 375 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(8) UniProt(9)
Polymorphisms
SNPs within 2kb(32 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001530 G-protein coupled receptor 34
References
(Earliest) J:56262 Schoneberg T, et al., A novel subgroup of class I G-protein-coupled receptors. Biochim Biophys Acta. 1999 Jul 7;1446(1-2):57-70
(Latest) J:168120 Liebscher I, et al., Altered immune response in mice deficient for the G protein-coupled receptor GPR34. J Biol Chem. 2011 Jan 21;286(3):2101-10
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory