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Gpr34
Gene Detail
Symbol

Name
ID
Gpr34
G protein-coupled receptor 34
MGI:1346334
Feature Type
protein coding gene
Genetic Map
Chromosome X
8.55 cM, cytoband A1.3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:13632089-13640856 bp, + strand
From VEGA annotation of GRCm38

  8768 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36174  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: GPR34
Protein SuperFamily: probable G protein-coupled receptor 34
Gene Tree: Gpr34

Human
homologs
GPR34, G protein-coupled receptor 34
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 2857
neXtProt AC: NX_Q9UPC5

Human Synonyms: LYPSR1

Human Chr (Location): Xp11.4; chrX:41688959-41697277 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele exhibit increased monocyte migration and susceptibility to type IV hypersensitivity and fungal infection.
 
Interactions
Gpr34 interacts with 119 markers (Mir1b, Mir17, Mir19a, ...)
Expression
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase gpr34 ; ZFIN gpr34b    NEW 
Molecular
reagents
All nucleic(15) cDNA(13) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000016906 (Evidence)
Ensembl Gene Model ENSMUSG00000040229 (Evidence)
Entrez Gene 23890 (Evidence)
UniGene 487326
DFCI TC1582815, TC1598763
DoTS DT.111033009, DT.55128522
NIA Mouse Gene Index U019726
Consensus CDS Project CCDS30028.1
International Mouse Phenotyping Consortium Status Gpr34
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016906 VEGA Gene Model | MGI Sequence Detail 8768 C57BL/6J ±  kb
transcript OTTMUST00000041027 VEGA | MGI Sequence Detail 2088 Not Applicable 
polypeptide OTTMUSP00000018373 VEGA | MGI Sequence Detail 375 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(8) UniProt(5)
Polymorphisms
SNPs within 2kb(32 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001530 G-protein coupled receptor 34
References
(Earliest) J:56262 Schoneberg T, et al., A novel subgroup of class I G-protein-coupled receptors. Biochim Biophys Acta. 1999 Jul 7;1446(1-2):57-70
(Latest) J:222307 Barnes MJ, et al., The lysophosphatidylserine receptor GPR174 constrains regulatory T cell development and function. J Exp Med. 2015 Jun 29;212(7):1011-20
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory