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Banf1 Gene Detail
Summary
  • Symbol
    Banf1
  • Name
    barrier to autointegration factor 1
  • Synonyms
    Bcrp1, C78287
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346330
    NCBI Gene: 23825
Location & Maps
more
  • Sequence Map
    Chr19:5364641-5366645 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2005 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.31 cM, cytoband A
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    BANF1, barrier to autointegration factor 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    BANF1, barrier to autointegration factor 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BAF, BCRP1, D14S1460, NGPS
  • Links
    NCBI Gene ID: 8815
    neXtProt AC: NX_O75531

  • Chr Location
    11q13.1; chr11:66002079-66004146 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human BANF1 associations

Human Disease Mouse Models
       Nestor-Guillermo Progeria Syndrome; NGPS   OMIM: 614008
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    76
  • Gene trapped
    72
  • Targeted
    4
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024844 Ensembl Gene Model | MGI Sequence Detail 2005 C57BL/6J ±  kb
transcript ENSMUST00000025762 Ensembl | MGI Sequence Detail 735 Not Applicable  
polypeptide ENSMUSP00000025762 Ensembl | MGI Sequence Detail 89 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    15 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000004637 barrier-to-autointegration factor
  • InterPro Domains
    IPR004122 Barrier- to-autointegration factor, BAF
Molecular
Reagents
less
  • All nucleic 105
    cDNA 105

    Microarray probesets 5
Other
Accession IDs
less
MGI:2147785
References
more
  • Summaries
    All 35
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:57554 Lee MS, et al., A previously unidentified host protein protects retroviral DNA from autointegration. Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1528-33
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory