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Gpc6
Gene Detail
 Symbol
Name
ID
Gpc6
glypican 6
MGI:1346322
Synonyms 6720429C22Rik
Feature Type protein coding gene
Genetic Map
Chromosome 14
60.34 cM, cytoband E4
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:116925297-117979529 bp, + strand
From VEGA annotation of GRCm38

  1054233 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55922  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: glypican
Gene Tree: Gpc6

Human
homologs
Human Homolog GPC6, glypican 6
NCBI Gene ID 10082
neXtProt AC  NX_Q9Y625
Human Synonyms  OMIMD1
Human Chr (Location)  13q32; chr13:93226825-94408020 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human GPC6
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(1) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Gpc6 interacts with 436 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process cell migration
Component anchored component of membrane, extracellular region, ...
Function heparan sulfate proteoglycan binding
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (3)    Tissues (3)    Images (2)
Theiler Stages: 16, 17
Assay TypeResults
RNA in situ 2
RT-PCR 1
cDNA source data(46)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(47) cDNA(46) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000018004 (Evidence)
Ensembl Gene ModelENSMUSG00000058571 (Evidence)
Entrez Gene23888 (Evidence)
UniGene440025
DFCITC1584382, TC1587681, TC1624200, TC1636954, TC1647488, TC1696934
DoTSDT.101269128, DT.101712151, DT.40153178, DT.97409368
NIA Mouse Gene IndexU015959
Consensus CDS ProjectCCDS27330.1, CCDS37008.1
International Mouse Knockout Project StatusGpc6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018004 VEGA Gene Model | MGI Sequence Detail 1054233 C57BL/6J ±  kb
transcript OTTMUST00000083121 VEGA | MGI Sequence Detail 2423 Not Applicable 
polypeptide OTTMUSP00000044609 VEGA | MGI Sequence Detail 565 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(6) UniProt(5)
Polymorphisms SNPs within 2kb(8371 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001863 Glypican
InterPro IPR019803 Glypican, conserved site
Protein Ontology PR:000008168 glypican-6
References (Earliest) J:57579 Veugelers M, et al., Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans. J Biol Chem. 1999 Sep 17;274(38):26968-77
(Latest) J:201656 de Wit J, et al., Unbiased discovery of glypican as a receptor for LRRTM4 in regulating excitatory synapse development. Neuron. 2013 Aug 21;79(4):696-711
All references(42)
Other
accession IDs
MGI:1924985, MGI:2145665

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory