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Srp54a Gene Detail
Summary
  • Symbol
    Srp54a
  • Name
    signal recognition particle 54A
  • Synonyms
    54kDa, 54K subunit of signal recognition particle, Srp54
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346087
    NCBI Gene: 24067
Location & Maps
more
  • Sequence Map
    Chr12:55089202-55112891 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23690 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 23.86 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SRP54, signal recognition particle 54
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SRP54, signal recognition particle 54
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 6729
    neXtProt AC: NX_P61011

  • Chr Location
    14q13.2; chr14:34982695-35029567 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2362
    1 human;2 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: SRP54
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    1
  • Chemically induced (other)
    1
  • Genomic Mutations
    1 involving Srp54a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073079 Ensembl Gene Model | MGI Sequence Detail 23690 C57BL/6J ±  kb
transcript ENSMUST00000021407 Ensembl | MGI Sequence Detail 1515 Not Applicable  
polypeptide ENSMUSP00000021407 Ensembl | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    60 from dbSNP Build 142
Protein
Information
less
  • Protein Ontology
    PR:000015625 signal recognition particle 54 kDa protein
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
References
more
  • Summaries
    All 17
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:25672 Bernstein HD, et al., Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle. Nature. 1989 Aug 10;340(6233):482-6
  • Latest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory