Tshz1
Gene Detail

Symbol Name ID

Tshz1 teashirt zinc finger family member 1 MGI:1346031

Synonyms

5730407I04Rik, D18Bwg1409e, Mtsh1, NY-CO-33, Sdccag33, teashirt1, Tsh1

Feature Type

protein coding gene

Genetic Map

Chromosome 18

57.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr18:84011627-84086404 bp, - strand From VEGA annotation of GRCm38   74778 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4227  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tshz1

Human homologs

Human Homolog		TSHZ1, teashirt zinc finger homeobox 1
NCBI Gene ID		10194
neXtProt AC		NX_Q6ZSZ6
Human Synonyms		CAA, NY-CO-33, SDCCAG33, TSH1
Human Chr (Location)		18q22.3; chr18:72922710-73001905 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TSHZ1

Alleles and phenotypes

All alleles(2) : Targeted(2)
 

Mice homozygous for a null allele die shortly after birth of respiratory distress, have defects in soft palate formation, have altered axial skeleton and have middle ear defects.

 

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	anterior/posterior pattern specification, middle ear morphogenesis, ...
Component	nucleus
Function	DNA binding, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (17 records)
Data Summary: Results (226)    Tissues (67)    Images (30)
Theiler Stages: 15, 17, 18, 19, 21, 23, 26

Assay Type	Results
RNA in situ	224
RT-PCR	2

cDNA source data(76)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(78) cDNA(76) Primer pair(2)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000040170 (Evidence)
Ensembl Gene Model	ENSMUSG00000046982 (Evidence)
Entrez Gene	110796 (Evidence)
UniGene	102136
DFCI	TC1578229, TC1602508, TC1623977, TC1672447
DoTS	DT.101280326, DT.101723335, DT.528559
NIA Mouse Gene Index	U038627
Consensus CDS Project	CCDS37876.1
International Mouse Knockout Project Status	Tshz1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000040170	VEGA Gene Model | MGI Sequence Detail	74778	C57BL/6J
transcript	OTTMUST00000104429	VEGA | MGI Sequence Detail	5656	Not Applicable
polypeptide	OTTMUSP00000058442	VEGA | MGI Sequence Detail	1084	Not Applicable

All sequences(41) RefSeq(3) UniProt(3)

Polymorphisms

SNPs(417 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001356	Homeodomain
InterPro	IPR009057	Homeodomain-like
InterPro	IPR027008	Teashirt family
InterPro	IPR026808	Teashirt homologue 1
InterPro	IPR007087	Zinc finger, C2H2
InterPro	IPR015880	Zinc finger, C2H2-like
Protein Ontology	PR:000016725	teashirt 1

References

(Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:196080 Elsen GE, et al., The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
All references(52)

Other accession IDs

MGD-MRK-33960, MGI:106268, MGI:1917748