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Tshz1
Gene Detail
 Symbol
Name
ID
Tshz1
teashirt zinc finger family member 1
MGI:1346031
Synonyms 5730407I04Rik, D18Bwg1409e, Mtsh1, NY-CO-33, Sdccag33, teashirt1, Tsh1
Feature Type protein coding gene
Genetic Map
Chromosome 18
57.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr18:84011628-84086404 bp, - strand
From VEGA annotation of GRCm38

  74777 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4227  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tshz1

Human
homologs
Human Homolog TSHZ1, teashirt zinc finger homeobox 1
NCBI Gene ID 10194
neXtProt AC  NX_Q6ZSZ6
Human Synonyms  CAA, NY-CO-33, SDCCAG33, TSH1
Human Chr (Location)  18q22.3; chr18:75210755-75289950 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human TSHZ1
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
 
Mice homozygous for a null allele die shortly after birth of respiratory distress, have defects in soft palate formation, have altered axial skeleton and have middle ear defects.
 
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process anterior/posterior pattern specification, middle ear morphogenesis, ...
Component nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (17 records)
Data Summary: Results (226)    Tissues (67)    Images (30)
Theiler Stages: 15, 17, 18, 19, 21, 23, 26
Assay TypeResults
RNA in situ 224
RT-PCR 2
cDNA source data(81)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(83) cDNA(81) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000040170 (Evidence)
Ensembl Gene ModelENSMUSG00000046982 (Evidence)
Entrez Gene110796 (Evidence)
UniGene102136
DFCITC1578229, TC1602508, TC1623977, TC1672447
DoTSDT.101280326, DT.101723335, DT.528559
NIA Mouse Gene IndexU038627
Consensus CDS ProjectCCDS37876.1
International Mouse Knockout Project StatusTshz1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000040170 VEGA Gene Model | MGI Sequence Detail 74777 C57BL/6J ±  kb
transcript OTTMUST00000104429 VEGA | MGI Sequence Detail 5655 Not Applicable 
polypeptide OTTMUSP00000058442 VEGA | MGI Sequence Detail 1084 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(5) UniProt(2)
Polymorphisms SNPs within 2kb(462 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR027008 Teashirt family
InterPro IPR026808 Teashirt homologue 1
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
Protein Ontology PR:000016725 teashirt homolog 1
References (Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:196080 Elsen GE, et al., The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
All references(51)
Other
accession IDs
MGD-MRK-33960, MGI:106268, MGI:1917748

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory