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Mab21l2
Gene Detail
Symbol

Name
ID
Mab21l2
mab-21-like 2 (C. elegans)
MGI:1346022
Feature Type
protein coding gene
Genetic Map
Chromosome 3
37.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:86545581-86548283 bp, - strand
From NCBI annotation of GRCm38

  2703 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7824  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Mab21l2

Human
homologs
Human Homolog MAB21L2, mab-21-like 2 (C. elegans)
NCBI Gene ID 10586
neXtProt AC  NX_Q9Y586
Human Synonyms  MCOPS14
Human Chr (Location)  4q31; chr4:150581925-150584693 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human MAB21L2
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix )
 
Homozygous mutation of this gene results in omphalocele and defects in ventral body wall formation resulting in death at mid-gestation. Mutants have impaired development of the retina and lens.
 
Interactions
Mab21l2 interacts with 224 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process camera-type eye development, embryonic body morphogenesis, ...
Component nucleus
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (143)    Tissues (111)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 143
cDNA source data(40)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(44) Genomic(1) cDNA(42) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000057777 (Evidence)
Entrez Gene23937 (Evidence)
UniGene389466
DFCITC1580671
DoTSDT.483528
Consensus CDS ProjectCCDS17447.1
International Mouse Knockout Project StatusMab21l2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 23937 NCBI Gene Model | MGI Sequence Detail 2703 C57BL/6J ±  kb
transcript NM_011839 RefSeq | MGI Sequence Detail 2703 C57BL/6 
polypeptide Q8BPP1 UniProt | EBI | MGI Sequence Detail 359 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(16 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024810 Mab-21 domain
InterPro IPR020950 Protein male abnormal 21-related
InterPro IPR000772 Ricin B lectin domain
Protein Ontology PR:000010035 protein mab-21-like 2
Graphical View of Protein Domain Structure
References
(Earliest) J:57575 Wong RL, et al., Genomic cloning and chromosomal localization of the mouse Mab21l2 locus. Cytogenet Cell Genet. 1999;86(1):21-4
(Latest) J:201042 Saito Y, et al., The septum transversum mesenchyme induces gall bladder development. Biol Open. 2013;2:779-788
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory