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Slco2a1 Gene Detail
Summary
  • Symbol
    Slco2a1
  • Name
    solute carrier organic anion transporter family, member 2a1
  • Synonyms
    2310021C19Rik, mPgt, Pgt, Slc21a2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346021
    NCBI Gene: 24059
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:102885686-102973201 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 54.72 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2792 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1346021
 protein coding gene Chr9:102865911-102973201 (+)
129S1/SvImJ ENSMUSG00200016182
 protein coding gene Chr9:100045546-100133489 (+)
A/J ENSMUSG00195015296
 protein coding gene Chr9:99262376-99350359 (+)
AKR/J ENSMUSG00220033887
 protein coding gene Chr9:99653062-99741074 (+)
BALB/cJ ENSMUSG00180022767
 protein coding gene Chr9:99579063-99667056 (+)
C3H/HeJ ENSMUSG00175011419
 protein coding gene Chr9:99921697-100009677 (+)
C57BL/6NJ ENSMUSG00215009105
 protein coding gene Chr9:99922504-100010529 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032584
 protein coding gene Chr9:98411486-98517730 (+)
CAST/EiJ ENSTCUG00005012557
 protein coding gene Chr9:99708590-99796644 (+)
CBA/J ENSMUSG00210014957
 protein coding gene Chr9:99778105-99866133 (+)
DBA/2J ENSMUSG00185010348
 protein coding gene Chr9:99928949-100016965 (+)
FVB/NJ ENSMUSG00205016698
 protein coding gene Chr9:99932775-100020832 (+)
JF1/MsJ ENSUMUG00000038968
 protein coding gene Chr9:99752793-99840933 (+)
LP/J ENSMUSG00230014960
 protein coding gene Chr9:100077004-100164999 (+)
NOD/ShiLtJ ENSMUSG00190027117
 protein coding gene Chr9:99564675-99652644 (+)
NZO/HlLtJ ENSMUSG00225018145
 protein coding gene Chr9:100297590-100385318 (+)
PWK/PhJ ENSLUMG00010023870
 protein coding gene Chr9:99682631-99779637 (+)
SPRET/EiJ ENSMSPG00010041121
 protein coding gene Chr9:101561881-101644562 (+)
WSB/EiJ ENSIUOG00005020711
 protein coding gene Chr9:98996611-99084554 (+)



Homology
more
  • Human Ortholog
    SLCO2A1, solute carrier organic anion transporter family member 2A1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLCO2A1, solute carrier organic anion transporter family member 2A1
  • Synonyms
    MATR1, OATP2A1, PGT, PHOAD, PHOAR2, SLC21A2
  • Links
    NCBI Gene ID: 6578
    UniProt: Q92959

  • Chr Location
    3q22.1-q22.2; chr3:133932699-134052184 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SLCO2A1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit preinatel or early psotnatal lethality due to a patent ductus arteriosus and abnormal protaglandin metabolism.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    771
  • Tissues
    173
  • cDNA Data
    16
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 24059 NCBI Gene Model | MGI Sequence Detail 87516 C57BL/6J ±  kb
    transcript NM_033314 RefSeq | MGI Sequence Detail 4451 ZRU/MplStud  
    polypeptide Q9EPT5 UniProt | EBI | MGI Sequence Detail 643 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 17
      Primer pair 2

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1915306
    References
    more
    • Summaries
      All 60
      Developmental Gene Expression 9
      Gene Ontology 8
      Phenotypes 20
    • Earliest
      J:57568 Pucci ML, et al., Cloning of mouse prostaglandin transporter PGT cDNA: species-specific substrate affinities. Am J Physiol. 1999 Sep;277(3 Pt 2):R734-41
    • Latest
      J:369572 Ben-Simon Y, et al., A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types. Cell. 2025 May 29;188(11):3045-3064.e23
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory