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Clpx
Gene Detail
Symbol

Name
ID
Clpx
caseinolytic mitochondrial matrix peptidase chaperone subunit
MGI:1346017
Feature Type
protein coding gene
Genetic Map
Chromosome 9
35.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:65294260-65330657 bp, + strand
From VEGA annotation of GRCm38

  36398 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4851  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Clpx

Human
homologs
Human Homolog CLPX, caseinolytic mitochondrial matrix peptidase chaperone subunit
NCBI Gene ID 10845
neXtProt AC  NX_O76031
Human Chr (Location)  15q22.31; chr15:65150446-65185404 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(2) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Clpx interacts with 194 markers (Mir1a-1, Mir1a-2, Mir17, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process ATP catabolic process, positive regulation of peptidase activity, ...
Component cytoplasm, endopeptidase Clp complex, ...
Function ATPase activity, ATP binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
cDNA source data(72)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(74) cDNA(72) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000031828 (Evidence)
Ensembl Gene ModelENSMUSG00000015357 (Evidence)
Entrez Gene270166 (Evidence)
UniGene30088
DFCITC1577767, TC1685523, TC1589013, TC1594912
DoTSDT.94197851, DT.531773, DT.110631898, DT.97387740, DT.101371178
NIA Mouse Gene IndexU010633
Consensus CDS ProjectCCDS23288.1, CCDS40669.1
International Mouse Knockout Project StatusClpx
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031828 VEGA Gene Model | MGI Sequence Detail 36398 C57BL/6J ±  kb
transcript OTTMUST00000078915 VEGA | MGI Sequence Detail 2885 Not Applicable 
polypeptide OTTMUSP00000042020 VEGA | MGI Sequence Detail 634 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(5) UniProt(11)
Polymorphisms
PCR(2) : SNPs within 2kb(196 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR003959 ATPase, AAA-type, core
InterPro IPR019489 Clp ATPase, C-terminal
InterPro IPR004487 Clp protease, ATP-binding subunit ClpX
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000005604 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
References
(Earliest) J:55436 Santagata S, et al., Molecular cloning and characterization of a mouse homolog of bacterial ClpX, a novel mammalian class II member of the Hsp100/Clp chaperone family. J Biol Chem. 1999 Jun 4;274(23):16311-9
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)
Other
accession IDs
MGI:2143186

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory