Clpx
Gene Detail

Symbol Name ID

Clpx caseinolytic peptidase X (E.coli) MGI:1346017

Feature Type

protein coding gene

Genetic Map

Chromosome 9

35.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr9:65294260-65330657 bp, + strand From VEGA annotation of GRCm38   36398 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4851  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Clpx

Human homologs

Human Homolog		CLPX, ClpX caseinolytic peptidase X homolog (E. coli)
NCBI Gene ID		10845
neXtProt AC		NX_O76031
Human Chr (Location)		15q22.31; chr15:65442784-65477563 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(1) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (20 annotations)

Process	ATP catabolic process, positive regulation of peptidase activity, ...
Component	mitochondrial endopeptidase Clp complex, mitochondrial inner membrane, ...
Function	ATPase activity, ATP binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

cDNA source data(80)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(82) cDNA(80) Primer pair(2)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000031828 (Evidence)
Ensembl Gene Model	ENSMUSG00000015357 (Evidence)
Entrez Gene	270166 (Evidence)
UniGene	30088
DFCI	TC1577767, TC1589013, TC1594912, TC1685523
DoTS	DT.101371178, DT.110631898, DT.531773, DT.94197851, DT.97387740
NIA Mouse Gene Index	U010633
Consensus CDS Project	CCDS23288.1, CCDS40669.1
International Mouse Knockout Project Status	Clpx

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031828	VEGA Gene Model | MGI Sequence Detail	36398	C57BL/6J
transcript	OTTMUST00000078915	VEGA | MGI Sequence Detail	2885	Not Applicable
polypeptide	OTTMUSP00000042020	VEGA | MGI Sequence Detail	634	Not Applicable

All sequences(52) RefSeq(4) UniProt(6)

Polymorphisms

PCR(2) : SNPs(147 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003593	AAA+ ATPase domain
InterPro	IPR013093	ATPase, AAA-2
InterPro	IPR019489	Clp ATPase, C-terminal
InterPro	IPR004487	Clp protease, ATP-binding subunit ClpX
Protein Ontology	PR:000005604	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial

References

(Earliest) J:55436 Santagata S, et al., Molecular cloning and characterization of a mouse homolog of bacterial ClpX, a novel mammalian class II member of the Hsp100/Clp chaperone family. J Biol Chem. 1999 Jun 4;274(23):16311-9
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)

Other accession IDs

MGI:2143186