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Clpx Gene Detail
Summary
  • Symbol
    Clpx
  • Name
    caseinolytic mitochondrial matrix peptidase chaperone subunit
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346017
    NCBI Gene: 270166
Location & Maps
more
  • Sequence Map
    Chr9:65294260-65330657 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      36398 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 35.22 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CLPX, caseinolytic mitochondrial matrix peptidase chaperone subunit
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CLPX, caseinolytic mitochondrial matrix peptidase chaperone subunit
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 10845
    neXtProt AC: NX_O76031

  • Chr Location
    15q22.31; chr15:65150446-65185404 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    2
  • Genomic Mutations
    1 involving Clpx
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031828 VEGA Gene Model | MGI Sequence Detail 36398 C57BL/6J ±  kb
transcript OTTMUST00000078915 VEGA | MGI Sequence Detail 2885 Not Applicable  
polypeptide OTTMUSP00000042020 VEGA | MGI Sequence Detail 634 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    189 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 74
    cDNA 72
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2143186
References
more
  • Summaries
    All 33
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:55436 Santagata S, et al., Molecular cloning and characterization of a mouse homolog of bacterial ClpX, a novel mammalian class II member of the Hsp100/Clp chaperone family. J Biol Chem. 1999 Jun 4;274(23):16311-9
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory