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Ppp2r4
Gene Detail
Symbol

Name
ID
Ppp2r4
protein phosphatase 2A activator, regulatory subunit B
MGI:1346006
Synonyms
2610042B21Rik, MGC:60706, MGC:7129, PR 53
Feature Type
protein coding gene
Genetic Map
Chromosome 2
21.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:30416039-30447806 bp, + strand
From VEGA annotation of GRCm38

  31768 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6149  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PPP2R4
Protein SuperFamily: phosphotyrosyl phosphatase activator
Gene Tree: Ppp2r4

Human
homologs
PPP2R4, protein phosphatase 2A activator, regulatory subunit 4
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 5524
neXtProt AC: NX_Q15257

Human Synonyms: PP2A, PR53, PTPA

Human Chr (Location): 9q34; chr9:129110945-129148946 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(126) : Gene trapped(123) Targeted(3)
Incidental mutations (data from CvDC )
Interactions
Ppp2r4 interacts with 139 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (34 annotations)
Process metabolic process, mitotic spindle organization in nucleus, ...
Component calcium channel complex, cytoplasm, ...
Function ATPase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(243)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ppp2r4 ; ZFIN ppp2r4    NEW 
Molecular
reagents
All nucleic(243) cDNA(243)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000016797 (Evidence)
Ensembl Gene Model ENSMUSG00000039515 (Evidence)
Entrez Gene 110854 (Evidence)
UniGene 275393
DFCI TC1573182
NIA Mouse Gene Index U001587
EC 5.2.1.8
Consensus CDS Project CCDS15883.1
International Mouse Phenotyping Consortium Status Ppp2r4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016797 VEGA Gene Model | MGI Sequence Detail 31768 C57BL/6J ±  kb
transcript OTTMUST00000040773 VEGA | MGI Sequence Detail 2586 Not Applicable 
polypeptide OTTMUSP00000018234 VEGA | MGI Sequence Detail 323 Not Applicable 

For the selected sequences
All sequences(120) RefSeq(4) UniProt(8)
Polymorphisms
SNPs within 2kb(196 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004327 Phosphotyrosyl phosphatase activator, PTPA
Protein Ontology PR:000013142 serine/threonine-protein phosphatase 2A regulatory subunit B'
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(39)
Other
accession IDs
MGI:1923815, MGI:2139462, MGI:2139539

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory