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Ppp2r4 Gene Detail
Summary
  • Symbol
    Ppp2r4
  • Name
    protein phosphatase 2A activator, regulatory subunit B
  • Synonyms
    2610042B21Rik, MGC:60706, MGC:7129, PR 53
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346006
    NCBI Gene: 110854
Location & Maps
more
  • Sequence Map
    Chr2:30416039-30447806 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      31768 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    PPP2R4, protein phosphatase 2A regulatory subunit 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PPP2R4, protein phosphatase 2A regulatory subunit 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    PP2A, PR53, PTPA
  • Links
    NCBI Gene ID: 5524
    neXtProt AC: NX_Q15257

  • Chr Location
    9q34; chr9:129110945-129148946 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    126
  • Gene trapped
    123
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016797 VEGA Gene Model | MGI Sequence Detail 31768 C57BL/6J ±  kb
transcript OTTMUST00000040773 VEGA | MGI Sequence Detail 2586 Not Applicable  
polypeptide OTTMUSP00000018234 VEGA | MGI Sequence Detail 323 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    196 from dbSNP Build 137
Protein
Information
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  • UniProt
    8 Sequences
  • EC
  • InterPro Domains
    IPR004327 Phosphotyrosyl phosphatase activator, PTPA
Molecular
Reagents
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  • All nucleic 243
    cDNA 243

    Microarray probesets 4
Other
Accession IDs
less
MGI:1923815, MGI:2139462, MGI:2139539
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory