About   Help   FAQ
Ppp2r4
Gene Detail
 Symbol
Name
ID
Ppp2r4
protein phosphatase 2A activator, regulatory subunit B
MGI:1346006
Synonyms 2610042B21Rik, MGC:60706, MGC:7129, PR 53
Feature Type protein coding gene
Genetic Map
Chromosome 2
21.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:30416039-30447806 bp, + strand
From VEGA annotation of GRCm38

  31768 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6149  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: phosphotyrosyl phosphatase activator
Gene Tree: Ppp2r4

Human
homologs
Human Homolog PPP2R4, protein phosphatase 2A activator, regulatory subunit 4
NCBI Gene ID 5524
neXtProt AC  NX_Q15257
Human Synonyms  PP2A, PR53, PTPA
Human Chr (Location)  9q34; chr9:129110949-129148946 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(126) : Gene trapped(123) Targeted(3)
Interactions
Ppp2r4 interacts with 139 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (31 annotations)
Process ATP catabolic process, mitotic spindle organization in nucleus, ...
Component calcium channel complex, cytoplasm, ...
Function ATPase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(243)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(243) cDNA(243)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000016797 (Evidence)
Ensembl Gene ModelENSMUSG00000039515 (Evidence)
Entrez Gene110854 (Evidence)
UniGene275393
DFCITC1573182
NIA Mouse Gene IndexU001587
EC5.2.1.8
Consensus CDS ProjectCCDS15883.1
International Mouse Knockout Project StatusPpp2r4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016797 VEGA Gene Model | MGI Sequence Detail 31768 C57BL/6J ±  kb
transcript OTTMUST00000040773 VEGA | MGI Sequence Detail 2586 Not Applicable 
polypeptide OTTMUSP00000018234 VEGA | MGI Sequence Detail 323 Not Applicable 

For the selected sequences
All sequences(115) RefSeq(4) UniProt(8)
Polymorphisms SNPs within 2kb(196 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004327 Phosphotyrosyl phosphatase activator, PTPA
Protein Ontology PR:000013142 serine/threonine-protein phosphatase 2A regulatory subunit B'
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(41)
Other
accession IDs
MGI:1923815, MGI:2139462, MGI:2139539

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory