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Coro2a Gene Detail
Summary
  • Symbol
    Coro2a
  • Name
    coronin, actin binding protein 2A
  • Synonyms
    9030208C03Rik, coronin 4, IR10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345966
    NCBI Gene: 107684
  • Gene Overview
    MyGene.info: CORO2A
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:46536937-46601929 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 24.87 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    390 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1345966
protein coding gene Chr4:46536937-46602202 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028261
protein coding gene Chr4:44855779-44921316 (-)
A/J MGP_AJ_G0028220
protein coding gene Chr4:43205433-43260417 (-)
AKR/J MGP_AKRJ_G0028170
protein coding gene Chr4:44265585-44328651 (-)
BALB/cJ MGP_BALBcJ_G0028240
protein coding gene Chr4:43311952-43369572 (-)
C3H/HeJ MGP_C3HHeJ_G0027961
protein coding gene Chr4:44868151-44928607 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028681
protein coding gene Chr4:46513574-46590232 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025990
protein coding gene Chr4:40584579-40639529 (-)
CAST/EiJ MGP_CASTEiJ_G0027400
protein coding gene Chr4:44429959-44493227 (-)
CBA/J MGP_CBAJ_G0027927
protein coding gene Chr4:47991647-48067957 (-)
DBA/2J MGP_DBA2J_G0028077
protein coding gene Chr4:43096358-43158677 (-)
FVB/NJ MGP_FVBNJ_G0028044
protein coding gene Chr4:42351940-42414402 (-)
LP/J MGP_LPJ_G0028176
protein coding gene Chr4:44904418-44977378 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028068
protein coding gene Chr4:51065418-51136708 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028716
protein coding gene Chr4:44482813-44552647 (-)
PWK/PhJ MGP_PWKPhJ_G0027125
protein coding gene Chr4:43201527-43258248 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026953
protein coding gene Chr4:43986035-44049321 (-)
WSB/EiJ MGP_WSBEiJ_G0027478
protein coding gene Chr4:44401302-44465263 (-)



Homology
more
  • Human Ortholog
    CORO2A, coronin 2A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CORO2A, coronin 2A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLIPINB, IR10, WDR2
  • Links
    NCBI Gene ID: 7464
    neXtProt AC: NX_Q92828
    UniProt: Q92828

  • Chr Location
    9q22.33; chr9:98120975-98192674 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 2546
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CORO2A
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 107684 NCBI Gene Model | MGI Sequence Detail 64993 C57BL/6J ±  kb
transcript NM_178893 RefSeq | MGI Sequence Detail 4112 C57BL/6  
polypeptide Q8C0P5 UniProt | EBI | MGI Sequence Detail 524 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    Genomic 2
    cDNA 24
    Other 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140332, MGI:2443441
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:50558 Okumura M, et al., Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein. DNA Cell Biol. 1998 Sep;17(9):779-87
  • Latest
    J:207835 Suo D, et al., Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival. Nat Neurosci. 2014 Jan;17(1):36-45

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory