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Coro1c
Gene Detail
Symbol

Name
ID
Coro1c
coronin, actin binding protein 1C
MGI:1345964
Synonyms
coronin 3
Feature Type
protein coding gene
Genetic Map
Chromosome 5
55.64 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:113842436-113908758 bp, - strand
From VEGA annotation of GRCm38

  66323 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56537  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: CORO1C
Gene Tree: Coro1c

Human
homologs
CORO1C, coronin, actin binding protein, 1C
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 23603
neXtProt AC: NX_Q9ULV4

Human Synonyms: HCRNN4

Human Chr (Location): 12q24.1; chr12:108645109-108731550 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(70) : Gene trapped(68) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Coro1c interacts with 300 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (36 annotations)
Process actin cortical patch assembly, actin cytoskeleton organization, ...
Component actin cytoskeleton, cell projection, ...
Function actin binding, actin filament binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (15)    Tissues (14)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 3
Northern blot 12
cDNA source data(245)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase coro1c ; ZFIN coro1ca    NEW 
Molecular
reagents
All nucleic(246) cDNA(246)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000036099 (Evidence)
Ensembl Gene Model ENSMUSG00000004530 (Evidence)
Entrez Gene 23790 (Evidence)
UniGene 260158
DFCI TC1573950, TC1590689
NIA Mouse Gene Index U014799, U134303, U147709
Consensus CDS Project CCDS19555.1
International Mouse Phenotyping Consortium Status Coro1c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036099 VEGA Gene Model | MGI Sequence Detail 66323 C57BL/6J ±  kb
transcript OTTMUST00000092768 VEGA | MGI Sequence Detail 3491 Not Applicable 
polypeptide OTTMUSP00000051342 VEGA | MGI Sequence Detail 474 Not Applicable 

For the selected sequences
All sequences(90) RefSeq(2) UniProt(9)
Polymorphisms
SNPs within 2kb(454 from dbSNP Build 137)    SNPs within 2kb including multiple locations(456)
Protein-related
information
ResourceIDDescription
InterPro IPR015505 Coronin
InterPro IPR027333 Coronin 1C
InterPro IPR015048 Domain of unknown function DUF1899
InterPro IPR015049 Domain of unknown function DUF1900
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000005762 coronin-1C
References
(Earliest) J:50558 Okumura M, et al., Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein. DNA Cell Biol. 1998 Sep;17(9):779-87
(Latest) J:219617 Williamson RC, et al., Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure. J Cell Sci. 2014 Oct 1;127(Pt 19):4292-307
All references(46)
Other
accession IDs
MGI:2141012, MGI:2141192, MGI:2141223

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory