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Coro1b Gene Detail
Summary
  • Symbol
    Coro1b
  • Name
    coronin, actin binding protein 1B
  • Synonyms
    coronin 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345963
    NCBI Gene: 23789
Location & Maps
more
  • Genetic Map
    Chromosome 19, 3.85 cM
  • Mapping Data
    2 experiments
Homology
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  • Human Ortholog
    CORO1B, coronin 1B
  • Vertebrate Orthologs
    6
  • Human Ortholog
    CORO1B, coronin 1B
    Orthology source: HomoloGene
  • Synonyms
    CORONIN-2
  • Links
    NCBI Gene ID: 57175
    neXtProt AC: NX_Q9BR76

  • Chr Location
    11q13.2; chr11:67438047-67443821 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    6 phenotype references
  • All Mutations and Alleles
    15
  • Gene trapped
    12
  • Targeted
    3
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit normal mast cell degranulation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028310 VEGA Gene Model | MGI Sequence Detail 5417 C57BL/6J ±  kb
transcript OTTMUST00000070153 VEGA | MGI Sequence Detail 1888 Not Applicable  
polypeptide OTTMUSP00000035725 VEGA | MGI Sequence Detail 484 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    19 from dbSNP Build 142
Protein
Information
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Molecular
Reagents
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  • All nucleic 206
    cDNA 206

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:50558 Okumura M, et al., Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein. DNA Cell Biol. 1998 Sep;17(9):779-87
  • Latest
    J:207835 Suo D, et al., Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival. Nat Neurosci. 2014 Jan;17(1):36-45

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory