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Slc35a1
Gene Detail
Symbol

Name
ID
Slc35a1
solute carrier family 35 (CMP-sialic acid transporter), member 1
MGI:1345622
Feature Type
protein coding gene
Genetic Map
Chromosome 4
16.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:34663257-34687438 bp, - strand
From VEGA annotation of GRCm38

  24182 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38181  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: SLC35A1
Protein SuperFamily: nucleotide-sugar transporter
Gene Tree: Slc35a1

Human
homologs
SLC35A1, solute carrier family 35 (CMP-sialic acid transporter), member A1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10559
neXtProt AC: NX_P78382

Human Synonyms: CDG2F, CMPST, CST, hCST

Human Chr (Location): 6q15; chr6:87472925-87512339 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SLC35A1

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in lethality before weaning.
 
Interactions
Slc35a1 interacts with 166 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (13)    Tissues (12)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
Northern blot 12
cDNA source data(64)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc35a1    NEW 
Molecular
reagents
All nucleic(66) cDNA(64) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000006413 (Evidence)
Ensembl Gene Model ENSMUSG00000028293 (Evidence)
Entrez Gene 24060 (Evidence)
UniGene 281885
DFCI TC1577342, TC1731358
DoTS DT.532699
NIA Mouse Gene Index U024932
Consensus CDS Project CCDS18030.1
International Mouse Phenotyping Consortium Status Slc35a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006413 VEGA Gene Model | MGI Sequence Detail 24182 C57BL/6J ±  kb
transcript OTTMUST00000014620 VEGA | MGI Sequence Detail 2039 Not Applicable 
polypeptide OTTMUSP00000006797 VEGA | MGI Sequence Detail 336 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(177 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007271 Nucleotide-sugar transporter
InterPro IPR021189 UDP/CMP-sugar transporter
InterPro IPR004689 UDP-galactose transporter
Protein Ontology PR:000015089 CMP-sialic acid transporter
References
(Earliest) J:57553 Eckhardt M, et al., Expression cloning of the Golgi CMP-sialic acid transporter. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7572-6
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(31)
Other
accession IDs
MGI:2140125, MGI:2140225

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory