Slc35a1
Gene Detail

Symbol Name ID

Slc35a1 solute carrier family 35 (CMP-sialic acid transporter), member 1 MGI:1345622

Feature Type

protein coding gene

Genetic Map

Chromosome 4

16.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr4:34663257-34687438 bp, - strand From VEGA annotation of GRCm38   24182 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Slc35a1 ± 2 cM)

Protein SuperFamily: nucleotide-sugar transporter
Gene Tree: Slc35a1

Human ortholog

SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 NCBI Gene ID 10559
Human Synonyms: CDG2F, CMPST, CST, hCST
Human Chr6:88182643-88222057 bp, + strand Reference GRCh37.p2 Primary Assembly
Human Diseases Associated with Human SLC35A1 (1)

Alleles and phenotypes

All alleles(4) : Gene trapped(4)
 

Homozygous mutation of this gene results in lethality before weaning.

 

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	carbohydrate transport, nucleotide-sugar transport, ...
Component	Golgi apparatus, Golgi membrane, ...
Function	nucleotide-sugar transmembrane transporter activity, sugar:hydrogen symporter activity

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (13)    Tissues (12)    Images (1)
Theiler Stages: 10, 18, 23, 25, 28

Assay Type	Results
RNA in situ	1
Northern blot	12

cDNA source data(63)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(65) cDNA(63) Primer pair(1) Other(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000006413 (Evidence)
Ensembl Gene Model	ENSMUSG00000028293 (Evidence)
Entrez Gene	24060 (Evidence)
UniGene	281885
DFCI	TC1577342, TC1731358
DoTS	DT.532699
NIA Mouse Gene Index	U024932
Consensus CDS Project	CCDS18030.1
International Mouse Knockout Project Status	Slc35a1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000006413	VEGA Gene Model | MGI Sequence Detail	24182	C57BL/6J
transcript	OTTMUST00000014620	VEGA | MGI Sequence Detail	2039	Not Applicable
polypeptide	OTTMUSP00000006797	VEGA | MGI Sequence Detail	336	Not Applicable

All sequences(34) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(161 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007271	Nucleotide-sugar transporter
InterPro	IPR021189	UDP/CMP-sugar transporter
InterPro	IPR004689	UDP-galactose transporter
Protein Ontology	PR:000015089	CMP-sialic acid transporter

References

(Earliest) J:57553 Eckhardt M, et al., Expression cloning of the Golgi CMP-sialic acid transporter. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7572-6
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)

Other accession IDs

MGI:2140125, MGI:2140225