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Slc25a1 Gene Detail
Summary
  • Symbol
    Slc25a1
  • Name
    solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
  • Synonyms
    1300019P08Rik, 2610100G11Rik, Dgsj, Slc20a3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345283
    NCBI Gene: 13358
  • Gene Overview
    MyGene.info: SLC25A1
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:17925223-17928219 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 11.11 cM, cytoband B1
  • Mapping Data
    11 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1345283
protein coding gene Chr16:17925211-17928219 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022599
protein coding gene Chr16:15114450-15117458 (-)
A/J MGP_AJ_G0022560
protein coding gene Chr16:14362209-14365217 (-)
AKR/J MGP_AKRJ_G0022537
protein coding gene Chr16:14920635-14923643 (-)
BALB/cJ MGP_BALBcJ_G0022563
protein coding gene Chr16:14516139-14519147 (-)
C3H/HeJ MGP_C3HHeJ_G0022330
protein coding gene Chr16:15069188-15072196 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023014
protein coding gene Chr16:15357587-15360595 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020534
protein coding gene Chr16:14418916-14421910 (-)
CAST/EiJ MGP_CASTEiJ_G0021858
protein coding gene Chr16:14987748-14990756 (-)
CBA/J MGP_CBAJ_G0022301
protein coding gene Chr16:16027506-16030514 (-)
DBA/2J MGP_DBA2J_G0022431
protein coding gene Chr16:14273458-14276466 (-)
FVB/NJ MGP_FVBNJ_G0022407
protein coding gene Chr16:14325406-14328414 (-)
LP/J MGP_LPJ_G0022498
protein coding gene Chr16:14896904-14899912 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022428
protein coding gene Chr16:15708825-15711833 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023025
protein coding gene Chr16:14866635-14869643 (-)
PWK/PhJ MGP_PWKPhJ_G0021601
protein coding gene Chr16:14532894-14535908 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021429
protein coding gene Chr16:14836628-14839637 (-)
WSB/EiJ MGP_WSBEiJ_G0021905
protein coding gene Chr16:14850297-14853305 (-)



Homology
more
  • Human Ortholog
    SLC25A1, solute carrier family 25 member 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SLC25A1, solute carrier family 25 member 1
    Orthology source: HGNC
  • Synonyms
    CTP, D2L2AD, SEA, SLC20A3
  • Links
    NCBI Gene ID: 6576
    neXtProt AC: NX_P53007
    UniProt: P53007

  • Chr Location
    22q11.21; chr22:19175575-19178863 (-)  GRCh38.p7

Human Diseases
less
  • References
    5 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    68 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003528 Ensembl Gene Model | MGI Sequence Detail 2997 C57BL/6J ±  kb
transcript ENSMUST00000003622 Ensembl | MGI Sequence Detail 1666 Not Applicable  
polypeptide ENSMUSP00000003622 Ensembl | MGI Sequence Detail 311 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 153
    Genomic 21
    cDNA 129
    Primer pair 3

    Microarray probesets 2
Other
Accession IDs
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MGI:1203504, MGI:1915693, MGI:1924027, MGI:2146385, MGI:892007
References
more
  • Summaries
    All 109
    Developmental Gene Expression 7
    Diseases 5
    Gene Ontology 8
    Phenotypes 68
  • Earliest
    J:38193 Galili N, et al., A region of mouse chromosome 16 is syntenic to the DiGeorge, velocardiofacial syndrome minimal critical region. (Correction: vol. 7(4):399). Genome Res. 1997 Jan;7(1):17-26
  • Latest
    J:265457 Zamponi E, et al., Nrf2 stabilization prevents critical oxidative damage in Down syndrome cells. Aging Cell. 2018 Oct;17(5):e12812

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory