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Slc30a1
Gene Detail
Symbol

Name
ID
Slc30a1
solute carrier family 30 (zinc transporter), member 1
MGI:1345281
Synonyms
C130040I11Rik, Znt1
Feature Type
protein coding gene
Genetic Map
Chromosome 1
97.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr1:191906767-191913247 bp, + strand
From VEGA annotation of GRCm38

  6481 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6681  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLC30A1
Protein SuperFamily: cation efflux protein
Gene Tree: Slc30a1

Human
homologs
SLC30A1, solute carrier family 30 (zinc transporter), member 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 7779
neXtProt AC: NX_Q9Y6M5

Human Synonyms: ZNT1, ZRC1

Human Chr (Location): 1q32.3; chr1:211575039-211578757 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous mutation of this gene results in embryonic lethality soon after implantation with embryonic growth arrest at the egg cylinder stage. Embryos from heterozygous females on a zinc deficient diet develop abnormally.
 
Phenotype Images(1)
Interactions
Slc30a1 interacts with 404 markers (Mir1b, Mir7-1, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (33 annotations)
Process cadmium ion transmembrane transport, calcium ion import, ...
Component cell, cytoplasm, ...
Function calcium channel inhibitor activity, cation transmembrane transporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (204)    Tissues (103)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 197
Northern blot 7
cDNA source data(36)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc30a1 ; ZFIN slc30a1a    NEW 
Molecular
reagents
All nucleic(39) Genomic(1) cDNA(36) Primer pair(1) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000021865 (Evidence)
Ensembl Gene Model ENSMUSG00000037434 (Evidence)
Entrez Gene 22782 (Evidence)
UniGene 9024
DFCI TC1586153, TC1605661
DoTS DT.485067
NIA Mouse Gene Index U001296
Consensus CDS Project CCDS15625.1
International Mouse Phenotyping Consortium Status Slc30a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021865 VEGA Gene Model | MGI Sequence Detail 6481 C57BL/6J ±  kb
transcript OTTMUST00000051885 VEGA | MGI Sequence Detail 5244 Not Applicable 
polypeptide OTTMUSP00000024495 VEGA | MGI Sequence Detail 503 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(4) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(65 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002524 Cation efflux protein
InterPro IPR027469 Cation efflux protein transmembrane domain
Protein Ontology PR:000015073 zinc transporter 1
References
(Earliest) J:23612 Palmiter RD, et al., Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. EMBO J. 1995 Feb 15;14(4):639-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(43)
Other
accession IDs
MGD-MRK-24139, MGI:103261, MGI:2138330

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory