Slc30a3
Gene Detail

Symbol Name ID

Slc30a3 solute carrier family 30 (zinc transporter), member 3 MGI:1345280

Synonyms

Znt3

Feature Type

protein coding gene

Genetic Map

Chromosome 5

16.97 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr5:31086106-31093615 bp, - strand From VEGA annotation of GRCm38   7510 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:74470  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: cation efflux protein
Gene Tree: Slc30a3

Human homologs

Human Homolog		SLC30A3, solute carrier family 30 (zinc transporter), member 3
NCBI Gene ID		7781
neXtProt AC		NX_Q99726
Human Synonyms		ZNT3
Human Chr (Location)		2p23.3; chr2:27477440-27485960 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

While zinc is absent from synaptic vesicles in homozygous null mice, inactivation of this locus does not affect brain morphology.

 

Gene Ontology (GO) classifications

All GO classifications: (21 annotations)

Process	cation transport, detoxification of zinc ion, ...
Component	cell junction, cytoplasm, ...
Function	cation transmembrane transporter activity

External Resources: FuncBase

Expression

Literature Summary: (6 records)
Data Summary: Results (212)    Tissues (70)    Images (21)
Theiler Stages: 23, 26, 28

Assay Type	Results
RNA in situ	212

cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(20) Genomic(1) cDNA(18) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000015164 (Evidence)
Ensembl Gene Model	ENSMUSG00000029151 (Evidence)
Entrez Gene	22784 (Evidence)
UniGene	1396
DFCI	TC1581507, TC1586945
DoTS	DT.487041
NIA Mouse Gene Index	U026056
Consensus CDS Project	CCDS51455.1
International Mouse Knockout Project Status	Slc30a3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000015164	VEGA Gene Model | MGI Sequence Detail	7510	C57BL/6J
transcript	OTTMUST00000035963	VEGA | MGI Sequence Detail	2089	Not Applicable
polypeptide	OTTMUSP00000016149	VEGA | MGI Sequence Detail	388	Not Applicable

All sequences(24) RefSeq(2) UniProt(4)

Polymorphisms

RFLP(3) : SNPs(7 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002524	Cation efflux protein
Protein Ontology	PR:000015076	zinc transporter 3

References

(Earliest) J:37242 Palmiter RD, et al., ZnT-3, a putative transporter of zinc into synaptic vesicles. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14934-9
(Latest) J:187545 Larimore J, et al., The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse. Mol Biol Cell. 2011 Dec;22(24):4854-67
All references(56)

Other accession IDs

MGD-MRK-36577, MGI:107997