About   Help   FAQ
Slc30a3
Gene Detail
Symbol

Name
ID
Slc30a3
solute carrier family 30 (zinc transporter), member 3
MGI:1345280
Synonyms
Znt3
Feature Type
protein coding gene
Genetic Map
Chromosome 5
16.97 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:31086106-31108237 bp, - strand
From VEGA annotation of GRCm38

  22132 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74470  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

Protein SuperFamily: cation efflux protein
Gene Tree: Slc30a3

Human
homologs
Human Homolog SLC30A3, solute carrier family 30 (zinc transporter), member 3
NCBI Gene ID 7781
neXtProt AC  NX_Q99726
Human Synonyms  ZNT3
Human Chr (Location)  2p23.3; chr2:27254572-27276146 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Radiation induced(2) Targeted(1)
Genomic Mutations involving Slc30a3 (2)
Incidental mutations (data from Mutagenetix , APF )
 
While zinc is absent from synaptic vesicles in homozygous null mice, inactivation of this locus does not affect brain morphology.
 
Alleles Annotated to Human Diseases(1)   
Interactions
Slc30a3 interacts with 159 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process cation transport, detoxification of zinc ion, ...
Component cell junction, cytoplasm, ...
Function cation transmembrane transporter activity
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (212)    Tissues (81)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 212
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(20) Genomic(1) cDNA(18) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000015164 (Evidence)
Ensembl Gene ModelENSMUSG00000029151 (Evidence)
Entrez Gene22784 (Evidence)
UniGene1396
DFCITC1586945, TC1581507
DoTSDT.487041
NIA Mouse Gene IndexU026056
Consensus CDS ProjectCCDS51455.1
International Mouse Knockout Project StatusSlc30a3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015164 VEGA Gene Model | MGI Sequence Detail 22132 C57BL/6J ±  kb
transcript OTTMUST00000035963 VEGA | MGI Sequence Detail 2089 Not Applicable 
polypeptide OTTMUSP00000016149 VEGA | MGI Sequence Detail 388 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(6) UniProt(17)
Polymorphisms
RFLP(3) : SNPs within 2kb(116 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002524 Cation efflux protein
InterPro IPR027469 Cation efflux protein transmembrane domain
Protein Ontology PR:000015076 zinc transporter 3
References
(Earliest) J:37242 Palmiter RD, et al., ZnT-3, a putative transporter of zinc into synaptic vesicles. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14934-9
(Latest) J:211082 Khan M, et al., Two-photon imaging of Zn2+ dynamics in mossy fiber boutons of adult hippocampal slices. Proc Natl Acad Sci U S A. 2014 May 6;111(18):6786-91
All references(59)
Other
accession IDs
MGD-MRK-36577, MGI:107997

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/11/2014
MGI 5.20
The Jackson Laboratory