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Slc29a2 Gene Detail
Summary
  • Symbol
    Slc29a2
  • Name
    solute carrier family 29 (nucleoside transporters), member 2
  • Synonyms
    Der12, ENT2, HNP36
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345278
    NCBI Gene: 13340
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5024006-5031971 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.23 cM, cytoband A
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    56 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1345278
protein coding gene Chr19:5024006-5031972 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024685
protein coding gene Chr19:1950197-1958156 (+)
A/J MGP_AJ_G0024651
protein coding gene Chr19:1842765-1850736 (+)
AKR/J MGP_AKRJ_G0024624
protein coding gene Chr19:1897805-1905758 (+)
BALB/cJ MGP_BALBcJ_G0024651
protein coding gene Chr19:1838988-1846957 (+)
C3H/HeJ MGP_C3HHeJ_G0024419
protein coding gene Chr19:1900158-1908125 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025098
protein coding gene Chr19:2007126-2015085 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022528
protein coding gene Chr19:1777665-1785818 (+)
CAST/EiJ MGP_CASTEiJ_G0023891
protein coding gene Chr19:1925930-1933886 (+)
CBA/J MGP_CBAJ_G0024390
protein coding gene Chr19:2087889-2095928 (+)
DBA/2J MGP_DBA2J_G0024518
protein coding gene Chr19:1833079-1841044 (+)
FVB/NJ MGP_FVBNJ_G0024485
protein coding gene Chr19:1833967-1841913 (+)
LP/J MGP_LPJ_G0024604
protein coding gene Chr19:1942316-1950279 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024515
protein coding gene Chr19:1970004-1977975 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025146
protein coding gene Chr19:1900465-1908428 (+)
PWK/PhJ MGP_PWKPhJ_G0023637
protein coding gene Chr19:1868973-1877217 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023442
protein coding gene Chr19:1883168-1894557 (+)
WSB/EiJ MGP_WSBEiJ_G0023953
protein coding gene Chr19:1903809-1911753 (+)



Homology
more
  • Human Ortholog
    SLC29A2, solute carrier family 29 member 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SLC29A2, solute carrier family 29 member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DER12, ENT2, HNP36
  • Links
    NCBI Gene ID: 3177
    neXtProt AC: NX_Q14542
    UniProt: Q14542

  • Chr Location
    11q13.2; chr11:66362521-66372476 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit normal adenosine uptake in erythrocytes and protection from acute lung injury.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024891 Ensembl Gene Model | MGI Sequence Detail 7966 C57BL/6J ±  kb
transcript ENSMUST00000025826 Ensembl | MGI Sequence Detail 2472 Not Applicable  
polypeptide ENSMUSP00000025826 Ensembl | MGI Sequence Detail 456 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 30
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-24063, MGI:103195
References
more
  • Summaries
    All 41
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:27223 Lanahan A, et al., Growth factor-induced delayed early response genes. Mol Cell Biol. 1992 Sep;12(9):3919-29
  • Latest
    J:244602 Song A, et al., Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent. Nat Commun. 2017 Feb 07;8:14108

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory