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Tenm3
Gene Detail
Symbol

Name
ID
Tenm3
teneurin transmembrane protein 3
MGI:1345183
Synonyms
2610100B16Rik, mKIAA1455, Odz3, Ten-m3
Feature Type
protein coding gene
Genetic Map
Chromosome 8
27.02 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:48227682-48844026 bp, - strand
From VEGA annotation of GRCm38

  616345 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22673  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tenm3

Human
homologs
Human Homolog TENM3, teneurin transmembrane protein 3
NCBI Gene ID 55714
neXtProt AC  NX_Q9P273
Human Synonyms  MCOPCB9, ODZ3, Ten-m3, TNM3
Human Chr (Location)  4q35.1; chr4:182144703-182803024 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human TENM3
Mutations,
alleles, and
phenotypes
All mutations/alleles(101) : Gene trapped(97) Targeted(4)
Incidental mutations (data from APF )
 
Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks.
 
Interactions
Tenm3 interacts with 303 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (15 records)
Data Summary: Results (254)    Tissues (188)    Images (43)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 11
RNA in situ 228
Western blot 2
RT-PCR 13
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(10) Primer pair(4) Other(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000021119 (Evidence)
Ensembl Gene ModelENSMUSG00000031561 (Evidence)
Entrez Gene23965 (Evidence)
DFCITC1602572, TC1579576, TC1616742, TC1619004
DoTSDT.483773, DT.99839523, DT.55236611, DT.60104976
NIA Mouse Gene IndexU029804
Consensus CDS ProjectCCDS22303.1
International Mouse Knockout Project StatusTenm3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021119 VEGA Gene Model | MGI Sequence Detail 616345 C57BL/6J ±  kb
transcript OTTMUST00000049977 VEGA | MGI Sequence Detail 9242 Not Applicable 
polypeptide OTTMUSP00000023259 VEGA | MGI Sequence Detail 2715 Not Applicable 

For the selected sequences
All sequences(96) RefSeq(38) UniProt(11)
Polymorphisms
SNPs within 2kb(3233 from dbSNP Build 137)    SNPs within 2kb including multiple locations(3235)
Protein-related
information
ResourceIDDescription
InterPro IPR008969 Carboxypeptidase-like, regulatory domain
InterPro IPR013032 EGF-like, conserved site
InterPro IPR000742 Epidermal growth factor-like domain
InterPro IPR022385 Rhs repeat-associated core
InterPro IPR011042 Six-bladed beta-propeller, TolB-like
InterPro IPR009471 Teneurin intracellular, N-terminal
InterPro IPR006530 YD repeat
Protein Ontology PR:000011608 teneurin-3
References
(Earliest) J:54528 Oohashi T, et al., Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues. J Cell Biol. 1999 May 3;145(3):563-77
(Latest) J:208462 Merlin S, et al., Deletion of Ten-m3 induces the formation of eye dominance domains in mouse visual cortex. Cereb Cortex. 2013 Apr;23(4):763-74
All references(56)
Other
accession IDs
MGI:1917577

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory