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Adam25 Gene Detail
Summary
  • Symbol
    Adam25
  • Name
    a disintegrin and metallopeptidase domain 25 (testase 2)
  • Synonyms
    testase 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345157
    NCBI Gene: 23793
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:40752208-40756176 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 23.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    36 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1345157
protein coding gene Chr8:40752208-40756187 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0033539
protein coding gene Chr8:38140282-38143557 (+)
AKR/J MGP_AKRJ_G0033461
protein coding gene Chr8:39228179-39256789 (+)
BALB/cJ MGP_BALBcJ_G0033534
protein coding gene Chr8:38213072-38259870 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0034049
protein coding gene Chr8:41095317-41171395 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030999
protein coding gene Chr8:34807662-34811607 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0033376
protein coding gene Chr8:37947127-37952204 (+)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ADAM20, ADAM metallopeptidase domain 20
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ADAM20, ADAM metallopeptidase domain 20
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 8748
    neXtProt AC: NX_O43506
    UniProt: O43506

  • Chr Location
    14q24.2; chr14:70520817-70564742 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071937 Ensembl Gene Model | MGI Sequence Detail 3969 C57BL/6J ±  kb
transcript ENSMUST00000096663 Ensembl | MGI Sequence Detail 2621 Not Applicable  
polypeptide ENSMUSP00000094420 Ensembl | MGI Sequence Detail 760 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Gene Ontology 3
  • Earliest
    J:56266 Zhu GZ, et al., Identification of four novel ADAMs with potential roles in spermatogenesis and fertilization. Gene. 1999 Jul 8;234(2):227-37
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory