Sept3
Gene Detail

Symbol Name ID

Sept3 septin 3 MGI:1345148

Synonyms

3110018K01Rik, B530002E20Rik, Sep3

Feature Type

protein coding gene

Genetic Map

Chromosome 15

38.56 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr15:82274935-82294442 bp, + strand From NCBI annotation of GRCm38   19508 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:99740  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: septin
Gene Tree: Sept3

Human homologs

Human Homolog		SEPT3, septin 3
NCBI Gene ID		55964
neXtProt AC		NX_Q9UH03
Human Synonyms		bK250D10.3, SEP3
Human Chr (Location)		22q13.2; chr22:42372931-42394225 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(4) Gene trapped(1)
 

Mice homozygous for a null allele exhibit a normal phenotype.

 

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	cell cycle, cell division
Component	cell junction, cytoplasm, ...
Function	GTP binding, nucleotide binding

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (182)    Tissues (80)    Images (43)
Theiler Stages: 11, 13, 15, 17, 19, 20, 21, 23, 24, 28

Assay Type	Results
RNA in situ	163
Northern blot	19

cDNA source data(97)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(98) cDNA(97) Other(1)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000022456 (Evidence)
Entrez Gene	24050 (Evidence)
UniGene	309707
DFCI	TC1578981, TC1605031, TC1626990, TC1627352, TC1631517
DoTS	DT.101358982, DT.101398799, DT.40182335, DT.55281874, DT.94403859, DT.97367013
NIA Mouse Gene Index	U016481
Consensus CDS Project	CCDS37157.1
International Mouse Knockout Project Status	Sept3

Sequences

Length	Strain/Species
genomic	24050	NCBI Gene Model | MGI Sequence Detail	19508	C57BL/6J
transcript	NM_011889	RefSeq | MGI Sequence Detail	4731	C57BL/6
polypeptide	Q9Z1S5	UniProt | EBI | MGI Sequence Detail	350	Not Applicable

All sequences(37) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(70 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000038	Cell division protein GTP binding
InterPro	IPR016491	Septin
InterPro	IPR008114	Septin 3
Protein Ontology	PR:000014655	neuronal-specific septin-3

Graphical View of Protein Domain Structure

References

(Earliest) J:47981 Xiong JW, et al., Large-scale screening for developmental genes in embryonic stem cells and embryoid bodies using retroviral entrapment vectors. Dev Dyn. 1998 Jun;212(2):181-97
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(38)

Other accession IDs

MGI:1925606, MGI:2146169, MGI:2442742