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Sept3 Gene Detail
Summary
  • Symbol
    Sept3
  • Name
    septin 3
  • Synonyms
    3110018K01Rik, B530002E20Rik, Sep3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345148
    NCBI Gene: 24050
  • Gene Overview
    MyGene.info: SEPT3
Location & Maps
more
  • Sequence Map
    Chr15:82274935-82294442 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19508 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 38.56 cM, cytoband E2
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    SEPT3, septin 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SEPT3, septin 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bK250D10.3, SEP3
  • Links
    NCBI Gene ID: 55964
    neXtProt AC: NX_Q9UH03

  • Chr Location
    22q13.2; chr22:41976927-41998221 (+)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 3 alleles in 3 genetic backgrounds
    1 phenotype from multigenic genotypes
    27 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    2
  • Targeted
    5
  • Genomic Mutations
    3 involving Sept3
  • Incidental Mutations
Mice homozygous for a null allele exhibit a normal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022456 Ensembl Gene Model | MGI Sequence Detail 19508 C57BL/6J ±  kb
transcript ENSMUST00000023095 Ensembl | MGI Sequence Detail 4731 Not Applicable  
polypeptide ENSMUSP00000023095 Ensembl | MGI Sequence Detail 337 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    199 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 97
    cDNA 96
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1925606, MGI:2146169, MGI:2442742
References
more
  • Summaries
    All 36
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 4
    Phenotypes 27
  • Earliest
    J:47981 Xiong JW, et al., Large-scale screening for developmental genes in embryonic stem cells and embryoid bodies using retroviral entrapment vectors. Dev Dyn. 1998 Jun;212(2):181-97
  • Latest
    J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory