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Sept3
Gene Detail
 Symbol
Name
ID
Sept3
septin 3
MGI:1345148
Synonyms 3110018K01Rik, B530002E20Rik, Sep3
Feature Type protein coding gene
Genetic Map
Chromosome 15
38.56 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr15:82274935-82294442 bp, + strand
From NCBI annotation of GRCm38

  19508 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:99740  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: septin
Gene Tree: Sept3

Human
homologs
Human Homolog SEPT3, septin 3
NCBI Gene ID 55964
neXtProt AC  NX_Q9UH03
Human Synonyms  bK250D10.3, SEP3
Human Chr (Location)  22q13.2; chr22:41976927-41998221 (+)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit a normal phenotype.
 
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell cycle, cell division
Component cell junction, cytoplasm, ...
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (182)    Tissues (80)    Images (43)
Theiler Stages: 11, 13, 15, 17, 19, 20, 21, 23, 24, 28
Assay TypeResults
RNA in situ 163
Northern blot 19
cDNA source data(96)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(97) cDNA(96) Other(1)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000022456 (Evidence)
Entrez Gene24050 (Evidence)
UniGene309707
DFCITC1578981, TC1605031, TC1626990, TC1627352, TC1631517
DoTSDT.101358982, DT.101398799, DT.40182335, DT.55281874, DT.94403859, DT.97367013
NIA Mouse Gene IndexU016481
Consensus CDS ProjectCCDS37157.1
International Mouse Knockout Project StatusSept3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 24050 NCBI Gene Model | MGI Sequence Detail 19508 C57BL/6J ±  kb
transcript NM_011889 RefSeq | MGI Sequence Detail 4731 C57BL/6 
polypeptide Q9Z1S5 UniProt | EBI | MGI Sequence Detail 350 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(16) UniProt(2)
Polymorphisms SNPs within 2kb(140 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000038 Cell division protein GTP binding
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR016491 Septin
InterPro IPR008114 Septin 3
Protein Ontology PR:000014655 neuronal-specific septin-3
Graphical View of Protein Domain Structure
References (Earliest) J:47981 Xiong JW, et al., Large-scale screening for developmental genes in embryonic stem cells and embryoid bodies using retroviral entrapment vectors. Dev Dyn. 1998 Jun;212(2):181-97
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(38)
Other
accession IDs
MGI:1925606, MGI:2146169, MGI:2442742

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory