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Sept3
Gene Detail
Symbol

Name
ID
Sept3
septin 3
MGI:1345148
Synonyms
3110018K01Rik, B530002E20Rik, Sep3
Feature Type
protein coding gene
Genetic Map
Chromosome 15
38.56 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr15:82274935-82294442 bp, + strand
From Ensembl annotation of GRCm38

  19508 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:99740  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: septin
Gene Tree: Sept3

Human
homologs
Human Homolog SEPT3, septin 3
NCBI Gene ID 55964
neXtProt AC  NX_Q9UH03
Human Synonyms  bK250D10.3, SEP3
Human Chr (Location)  22q13.2; chr22:41976927-41998221 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(1) Radiation induced(1) Targeted(4)
Genomic Mutations involving Sept3 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit a normal phenotype.
 
Interactions
Sept3 interacts with 392 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell cycle, cell division
Component cell junction, cytoplasm, ...
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (182)    Tissues (80)    Images (43)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 163
Northern blot 19
cDNA source data(96)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(97) cDNA(96) Other(1)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000022456 (Evidence)
Entrez Gene24050 (Evidence)
UniGene309707
DFCITC1605031, TC1626990, TC1578981, TC1631517, TC1627352
DoTSDT.101398799, DT.101358982, DT.94403859, DT.97367013, DT.40182335, DT.55281874
NIA Mouse Gene IndexU016481
Consensus CDS ProjectCCDS37157.1
International Mouse Knockout Project StatusSept3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022456 Ensembl Gene Model | MGI Sequence Detail 19508 C57BL/6J ±  kb
transcript ENSMUST00000116423 Ensembl | MGI Sequence Detail 2467 Not Applicable 
polypeptide ENSMUSP00000112124 Ensembl | MGI Sequence Detail 337 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(16) UniProt(3)
Polymorphisms
SNPs within 2kb(140 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000038 Cell division protein GTP binding
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR016491 Septin
InterPro IPR008114 Septin 3
Protein Ontology PR:000014655 neuronal-specific septin-3
References
(Earliest) J:47981 Xiong JW, et al., Large-scale screening for developmental genes in embryonic stem cells and embryoid bodies using retroviral entrapment vectors. Dev Dyn. 1998 Jun;212(2):181-97
(Latest) J:186260 Yoshida A, et al., Localization of septin proteins in the mouse cochlea. Hear Res. 2012 Jul;289(1-2):40-51
All references(38)
Other
accession IDs
MGI:1925606, MGI:2146169, MGI:2442742

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory