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Sra1
Gene Detail
Symbol

Name
ID
Sra1
steroid receptor RNA activator 1
MGI:1344414
Synonyms
Srap
Feature Type
protein coding gene
Genetic Map
Chromosome 18
19.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:36666681-36671196 bp, - strand
From VEGA annotation of GRCm38

  4516 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11906  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SRA1
Gene Tree: Sra1

Human
homologs
SRA1, steroid receptor RNA activator 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10011
neXtProt AC: NX_Q9HD15

Human Synonyms: pp7684, SRA, SRAP, STRAA1

Human Chr (Location): 5q31.3; chr5:140550067-140558093 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(3) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice are protected against diet-induced obesity.
 
Interactions
Sra1 interacts with 88 markers (Mir7-2, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process cell differentiation, cell proliferation, ...
Component cell leading edge, cytoplasm, ...
Function DNA binding, ligand-dependent nuclear receptor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (44)    Tissues (44)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 44
cDNA source data(109)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase sra1 ; ZFIN sra1    NEW 
Molecular
reagents
All nucleic(109) cDNA(109)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000038237 (Evidence)
Ensembl Gene Model ENSMUSG00000006050 (Evidence)
Entrez Gene 24068 (Evidence)
UniGene 29058
DFCI TC1707133, TC1645868, TC1575286
DoTS DT.40187519, DT.101384540, DT.101134901, DT.535806, DT.94299486, DT.94299464
NIA Mouse Gene Index U038339
Consensus CDS Project CCDS29156.2
International Mouse Phenotyping Consortium Status Sra1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000038237 VEGA Gene Model | MGI Sequence Detail 4516 C57BL/6J ±  kb
transcript OTTMUST00000098450 VEGA | MGI Sequence Detail 2360 Not Applicable 
polypeptide OTTMUSP00000055340 VEGA | MGI Sequence Detail 232 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(5)
Polymorphisms
SNPs within 2kb(40 from dbSNP Build 137)    SNPs within 2kb including multiple locations(44)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000015605 steroid receptor RNA activator 1
References
(Earliest) J:54002 Lanz RB, et al., A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell. 1999 Apr 2;97(1):17-27
(Latest) J:214131 Liu S, et al., SRA gene knockout protects against diet-induced obesity and improves glucose tolerance. J Biol Chem. 2014 May 9;289(19):13000-9
All references(38)
Other
accession IDs
MGI:2147187

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory