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Ubd
Gene Detail
Symbol

Name
ID
Ubd
ubiquitin D
MGI:1344410
Synonyms
Diubiquitin, FAT10
Feature Type
protein coding gene
Genetic Map
Chromosome 17
19.16 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:37193892-37196095 bp, + strand
From VEGA annotation of GRCm38

  2204 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4665  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog

HCOP human homology predictions: UBD
Gene Tree: Ubd

Human
homologs
UBD, ubiquitin D
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 10537
neXtProt AC: NX_O15205

Human Synonyms: FAT10, GABBR1, UBD-3

Human Chr (Location): 6p21.3; chr6:29555612-29559925 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , CvDC )
 
Mice hompzygous for disruptions in this gene show an increased susceptibility to low doses of endotoxin and increased apoptosis among lymphocytes but are otherwise normal.
 
Interactions
Ubd interacts with 65 markers (Mir7-2, Mir7b, Mir27a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process aggresome assembly, myeloid dendritic cell differentiation, ...
Component aggresome, cytoplasm, ...
Function proteasome binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (1)    Tissues (1)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000037330 (Evidence)
Ensembl Gene Model ENSMUSG00000035186 (Evidence)
Entrez Gene 24108 (Evidence)
UniGene 140210
DFCI TC1585039
DoTS DT.487277
NIA Mouse Gene Index U017955
Consensus CDS Project CCDS28737.1
International Mouse Phenotyping Consortium Status Ubd
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037330 VEGA Gene Model | MGI Sequence Detail 2204 C57BL/6J ±  kb
transcript OTTMUST00000096338 VEGA | MGI Sequence Detail 931 Not Applicable 
polypeptide OTTMUSP00000053809 VEGA | MGI Sequence Detail 162 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(42 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000626 Ubiquitin
InterPro IPR019956 Ubiquitin subgroup
Protein Ontology PR:000016964 ubiquitin D
References
(Earliest) J:54530 Liu YC, et al., A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4313-8
(Latest) J:208623 Canaan A, et al., Extended lifespan and reduced adiposity in mice lacking the FAT10 gene. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5313-8
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory