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C1ql1 Gene Detail
Summary
  • Symbol
    C1ql1
  • Name
    complement component 1, q subcomponent-like 1
  • Synonyms
    C1qrf
  • Feature Type
    protein coding gene
  • IDs
    MGI:1344400
    NCBI Gene: 23829
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:102830090-102837514 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 66.48 cM, cytoband D
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1344400
protein coding gene Chr11:102830090-102837542 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019251
protein coding gene Chr11:105973132-105980555 (-)
A/J MGP_AJ_G0019219
protein coding gene Chr11:101482965-101490397 (-)
AKR/J MGP_AKRJ_G0019188
protein coding gene Chr11:104616867-104624290 (-)
BALB/cJ MGP_BALBcJ_G0019193
protein coding gene Chr11:101959747-101967171 (-)
C3H/HeJ MGP_C3HHeJ_G0019002
protein coding gene Chr11:104843943-104851366 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019642
protein coding gene Chr11:109253639-109261063 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017268
protein coding gene Chr11:98906655-98914022 (-)
CAST/EiJ MGP_CASTEiJ_G0018556
protein coding gene Chr11:105851228-105858637 (-)
CBA/J MGP_CBAJ_G0018971
protein coding gene Chr11:113794261-113801698 (-)
DBA/2J MGP_DBA2J_G0019083
protein coding gene Chr11:100997472-101004895 (-)
FVB/NJ MGP_FVBNJ_G0019073
protein coding gene Chr11:100539914-100547336 (-)
LP/J MGP_LPJ_G0019152
protein coding gene Chr11:106491568-106498991 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019104
protein coding gene Chr11:113224485-113231909 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019680
protein coding gene Chr11:104998751-105006174 (-)
PWK/PhJ MGP_PWKPhJ_G0018319
protein coding gene Chr11:102069737-102077148 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018111
protein coding gene Chr11:104759238-104766706 (-)
WSB/EiJ MGP_WSBEiJ_G0018605
protein coding gene Chr11:104994345-105001775 (-)



Homology
more
  • Human Ortholog
    C1QL1, complement C1q like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C1QL1, complement C1q like 1
  • Synonyms
    C1QRF, C1QTNF14, CRF, CTRP14
  • Links
    NCBI Gene ID: 10882
    neXtProt AC: NX_O75973
    UniProt: O75973

  • Chr Location
    17q21.31; chr17:44959693-44968276 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit impaired motor learning with alterned climbing fiber electrophysiology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045532 Ensembl Gene Model | MGI Sequence Detail 7425 C57BL/6J ±  kb
transcript ENSMUST00000057849 Ensembl | MGI Sequence Detail 1473 Not Applicable  
polypeptide ENSMUSP00000050469 Ensembl | MGI Sequence Detail 258 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 8
    Primer pair 2
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:51998 Berube NG, et al., Cloning and characterization of CRF, a novel C1q-related factor, expressed in areas of the brain involved in motor function. Brain Res Mol Brain Res. 1999 Jan 8;63(2):233-40
  • Latest
    J:307108 Biswas J, et al., C1ql1 is expressed in adult outer hair cells of the cochlea in a tonotopic gradient. PLoS One. 2021;16(5):e0251412

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory