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Chd3 Gene Detail
Summary
  • Symbol
    Chd3
  • Name
    chromodomain helicase DNA binding protein 3
  • Synonyms
    2600010P09Rik, Chd7, Mi-2 alpha, Prp7, Prp9-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1344395
    NCBI Gene: 216848
  • Gene Overview
    MyGene.info: CHD3
Location & Maps
more
  • Sequence Map
    Chr11:69343273-69369406 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26134 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 42.53 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CHD3, chromodomain helicase DNA binding protein 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CHD3, chromodomain helicase DNA binding protein 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    Mi-2a, Mi2-ALPHA, ZFH
  • Links
    NCBI Gene ID: 1107
    neXtProt AC: NX_Q12873

  • Chr Location
    17p13.1; chr17:7884776-7912757 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 62693
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CHD3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Gene trapped
    7
  • Targeted
    3
  • Genomic Mutations
    1 involving Chd3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005975 VEGA Gene Model | MGI Sequence Detail 26134 C57BL/6J ±  kb
transcript OTTMUST00000013358 VEGA | MGI Sequence Detail 7261 Not Applicable  
polypeptide OTTMUSP00000006184 VEGA | MGI Sequence Detail 2055 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    161 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 252
    cDNA 251
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1919700, MGI:1934942
References
more
  • Summaries
    All 37
    Developmental Gene Expression 8
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:44866 Ermekova KS, et al., The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled. J Biol Chem. 1997 Dec 26;272(52):32869-77
  • Latest
    J:194303 D R D, et al., Mi-2/NuRD is required in renal progenitor cells during embryonic kidney development. Dev Biol. 2013 Mar 15;375(2):105-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory