Oasl2
Gene Detail

Symbol Name ID

Oasl2 2'-5' oligoadenylate synthetase-like 2 MGI:1344390

Synonyms

M1204, Mmu-OASL

Feature Type

protein coding gene

Genetic Map

Chromosome 5

55.99 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr5:114896936-114912234 bp, + strand From VEGA annotation of GRCm38   15299 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:128369  Vertebrate Homology Class
1 mouse; 1 rat; 1 dog; 1 chicken

Gene Tree: Oasl2

Alleles and phenotypes

All alleles(9) : Targeted(1) Gene trapped(8)

Gene Ontology (GO) classifications

All GO classifications: (19 annotations)

Process	defense response to virus, immune response, ...
Component	cellular_component
Function	2'-5'-oligoadenylate synthetase activity, ATP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (40)    Tissues (26)    Images (17)
Theiler Stages: 19, 23, 28

Assay Type	Results
RNA in situ	40

cDNA source data(101)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(103) cDNA(103)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000014606 (Evidence)
Ensembl Gene Model	ENSMUSG00000029561 (Evidence)
Entrez Gene	23962 (Evidence)
UniGene	228363
DFCI	TC1575566
DoTS	DT.55100625, DT.97412521, DT.97412525
NIA Mouse Gene Index	U006038
EC	2.7.7.84
Consensus CDS Project	CCDS39226.1
International Mouse Knockout Project Status	Oasl2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000014606	VEGA Gene Model | MGI Sequence Detail	15299	C57BL/6J
transcript	OTTMUST00000034639	VEGA | MGI Sequence Detail	3123	Not Applicable
polypeptide	OTTMUSP00000015514	VEGA | MGI Sequence Detail	508	Not Applicable

All sequences(49) RefSeq(2) UniProt(7)

Polymorphisms

SNPs(34 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR026774	2'-5'-oligoadenylate synthase
InterPro	IPR018952	2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal
InterPro	IPR006117	2-5-oligoadenylate synthetase, conserved site
InterPro	IPR006116	2-5-oligoadenylate synthetase, N-terminal
InterPro	IPR000626	Ubiquitin
InterPro	IPR019955	Ubiquitin supergroup
Protein Ontology	PR:000012103	54 kDa 2'-5'-oligoadenylate synthetase-like protein 2

References

(Earliest) J:56109 Tiefenthaler M, et al., M1204, a novel 2',5' oligoadenylate synthetase with a ubiquitin-like extension, is induced during maturation of murine dendritic cells. J Immunol. 1999 Jul 15;163(2):760-5
(Latest) J:192649 Kristiansen H, et al., The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities. J Interferon Cytokine Res. 2011 Jan;31(1):41-7
All references(35)