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Oasl2
Gene Detail
Symbol

Name
ID
Oasl2
2'-5' oligoadenylate synthetase-like 2
MGI:1344390
Synonyms
M1204, Mmu-OASL
Feature Type
protein coding gene
Genetic Map
Chromosome 5
55.99 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:114896936-114912234 bp, + strand
From VEGA annotation of GRCm38

  15299 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128369  Vertebrate Homology Class
1 mouse; 1 rat; 1 dog; 1 chicken

Gene Tree: Oasl2

Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(8) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Oasl2 interacts with 222 markers (Mir1a-1, Mir1a-2, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process defense response to virus, immune response, ...
Component cellular_component
Function 2'-5'-oligoadenylate synthetase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (40)    Tissues (26)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 40
cDNA source data(98)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(100) cDNA(100)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000014606 (Evidence)
Ensembl Gene ModelENSMUSG00000029561 (Evidence)
Entrez Gene23962 (Evidence)
UniGene228363
DFCITC1575566
DoTSDT.55100625, DT.97412521, DT.97412525
NIA Mouse Gene IndexU006038
EC2.7.7.84
Consensus CDS ProjectCCDS39226.1
International Mouse Knockout Project StatusOasl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014606 VEGA Gene Model | MGI Sequence Detail 15299 C57BL/6J ±  kb
transcript OTTMUST00000034639 VEGA | MGI Sequence Detail 3123 Not Applicable 
polypeptide OTTMUSP00000015514 VEGA | MGI Sequence Detail 508 Not Applicable 

For the selected sequences
All sequences(55) RefSeq(8) UniProt(7)
Polymorphisms
SNPs within 2kb(112 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026774 2'-5'-oligoadenylate synthase
InterPro IPR018952 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal
InterPro IPR006117 2-5-oligoadenylate synthetase, conserved site
InterPro IPR006116 2-5-oligoadenylate synthetase, N-terminal
InterPro IPR000626 Ubiquitin
Protein Ontology PR:000012103 54 kDa 2'-5'-oligoadenylate synthetase-like protein 2
References
(Earliest) J:56109 Tiefenthaler M, et al., M1204, a novel 2',5' oligoadenylate synthetase with a ubiquitin-like extension, is induced during maturation of murine dendritic cells. J Immunol. 1999 Jul 15;163(2):760-5
(Latest) J:192649 Kristiansen H, et al., The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities. J Interferon Cytokine Res. 2011 Jan;31(1):41-7
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory