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Arih1 Gene Detail
Summary
  • Symbol
    Arih1
  • Name
    ariadne RBR E3 ubiquitin protein ligase 1
  • Synonyms
    UIP77
  • Feature Type
    protein coding gene
  • IDs
    MGI:1344363
    NCBI Gene: 23806
  • Gene Overview
    MyGene.info: ARIH1
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:59388554-59486659 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 32.01 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    329 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1344363
 protein coding gene Chr9:59388258-59486659 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034899
 protein coding gene Chr9:58733271-58833318 (-)
A/J MGP_AJ_G0034880
 protein coding gene Chr9:56847975-56947476 (-)
AKR/J MGP_AKRJ_G0034809
 protein coding gene Chr9:58163789-58264465 (-)
BALB/cJ MGP_BALBcJ_G0034872
 protein coding gene Chr9:56586003-56687824 (-)
C3H/HeJ MGP_C3HHeJ_G0034582
 protein coding gene Chr9:58662298-58761067 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035391
 protein coding gene Chr9:60361630-60462253 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032302
 protein coding gene Chr9:56582406-56681265 (-)
CAST/EiJ MGP_CASTEiJ_G0033903
 protein coding gene Chr9:58741321-58844252 (-)
CBA/J MGP_CBAJ_G0034553
 protein coding gene Chr9:62489939-62595465 (-)
DBA/2J MGP_DBA2J_G0034712
 protein coding gene Chr9:56668531-56768331 (-)
FVB/NJ MGP_FVBNJ_G0034654
 protein coding gene Chr9:55923566-56026900 (-)
LP/J MGP_LPJ_G0034795
 protein coding gene Chr9:59038405-59141750 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034697
 protein coding gene Chr9:63916080-64027499 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035413
 protein coding gene Chr9:58166555-58273904 (-)
PWK/PhJ MGP_PWKPhJ_G0033607
 protein coding gene Chr9:56722439-56823036 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033442
 protein coding gene Chr9:58445968-58554120 (-)
WSB/EiJ MGP_WSBEiJ_G0034016
 protein coding gene Chr9:58102820-58210280 (-)



Homology
more
  • Human Ortholog
    ARIH1, ariadne RBR E3 ubiquitin protein ligase 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ARIH1, ariadne RBR E3 ubiquitin protein ligase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARI, HARI, HHARI, UBCH7BP
  • Links
    NCBI Gene ID: 25820
    neXtProt AC: NX_Q9Y4X5
    UniProt: Q9Y4X5

  • Chr Location
    15q24.1; chr15:72474282-72586563 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    2
  • Tissues
    1
  • cDNA Data
    211
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 23806 NCBI Gene Model | MGI Sequence Detail 98106 C57BL/6J ±  kb
transcript NM_019927 RefSeq | MGI Sequence Detail 6435 C57BL/6  
polypeptide Q9Z1K5 UniProt | EBI | MGI Sequence Detail 555 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 212
    cDNA 211
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:2143211
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:56275 Martinez-Noel G, et al., A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4. FEBS Lett. 1999 Jul 9;454(3):257-61
  • Latest
    J:244873 Kathania M, et al., Ndfip1 regulates itch ligase activity and airway inflammation via UbcH7. J Immunol. 2015 Mar 01;194(5):2160-7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/08/2019
MGI 6.14 		The Jackson Laboratory