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Car14 Gene Detail
Summary
  • Symbol
    Car14
  • Name
    carbonic anhydrase 14
  • Synonyms
    CA XIV
  • Feature Type
    protein coding gene
  • IDs
    MGI:1344341
    NCBI Gene: 23831
  • Gene Overview
    MyGene.info: CA14
Location & Maps
more
  • Sequence Map
    Chr3:95897768-95904691 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6924 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 41.48 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CA14, carbonic anhydrase 14
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CA14, carbonic anhydrase 14
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CAXiV
  • Links
    NCBI Gene ID: 23632
    neXtProt AC: NX_Q9ULX7

  • Chr Location
    1q21; chr1:150257159-150265078 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    15 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Car14
  • Incidental Mutations
Mice homozygous for a knock-out allele are viable and display normal growth, health and fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022182 VEGA Gene Model | MGI Sequence Detail 6924 C57BL/6J ±  kb
transcript OTTMUST00000052679 VEGA | MGI Sequence Detail 1709 Not Applicable  
polypeptide OTTMUSP00000025013 VEGA | MGI Sequence Detail 337 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    6 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 41
    cDNA 40
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
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MGI:2139990
References
more
  • Summaries
    All 40
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 15
  • Earliest
    J:55432 Mori K, et al., Isolation and characterization of CA XIV, a novel membrane-bound carbonic anhydrase from mouse kidney. J Biol Chem. 1999 May 28;274(22):15701-5
  • Latest
    J:216097 Reibring CG, et al., Expression patterns and subcellular localization of carbonic anhydrases are developmentally regulated during tooth formation. PLoS One. 2014;9(5):e96007

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory