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Mid2 Gene Detail
Summary
  • Symbol
    Mid2
  • Name
    midline 2
  • Synonyms
    FXY2, Trim1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1344333
    NCBI Gene: 23947
  • Gene Overview
    MyGene.info: MID2
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:140664599-140767715 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 61.35 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    431 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1344333
protein coding gene ChrX:140664304-140767715 (.)
129S1/SvImJ MGP_129S1SvImJ_G0036136
protein coding gene ChrX:138224560-138337594 (+)
A/J MGP_AJ_G0036114
protein coding gene ChrX:137599140-137711208 (+)
AKR/J MGP_AKRJ_G0036039
protein coding gene ChrX:142006530-142121196 (+)
BALB/cJ MGP_BALBcJ_G0036104
protein coding gene ChrX:135907265-136015838 (+)
C3H/HeJ MGP_C3HHeJ_G0035813
protein coding gene ChrX:138236245-138345212 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036629
protein coding gene ChrX:142265639-142368306 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033453
protein coding gene ChrX:129318486-129416959 (+)
CAST/EiJ MGP_CASTEiJ_G0035104
protein coding gene ChrX:119057024-119159953 (+)
CBA/J MGP_CBAJ_G0035790
protein coding gene ChrX:146641984-146756758 (+)
DBA/2J MGP_DBA2J_G0035947
protein coding gene ChrX:136736699-136841482 (+)
FVB/NJ MGP_FVBNJ_G0035881
protein coding gene ChrX:135971714-136076089 (+)
LP/J MGP_LPJ_G0036038
protein coding gene ChrX:139175421-139274996 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035918
protein coding gene ChrX:154157638-154282749 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036665
protein coding gene ChrX:137528364-137638234 (+)
PWK/PhJ MGP_PWKPhJ_G0034797
protein coding gene ChrX:115945919-116051098 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034623
protein coding gene ChrX:119594748-119713319 (+)
WSB/EiJ MGP_WSBEiJ_G0035239
protein coding gene ChrX:135846362-135953636 (+)



Homology
more
  • Human Ortholog
    MID2, midline 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    MID2, midline 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FXY2, MRX101, RNF60, TRIM1
  • Links
    NCBI Gene ID: 11043
    neXtProt AC: NX_Q9UJV3
    UniProt: Q9UJV3

  • Chr Location
    Xq22.3; chrX:107820961-107931637 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000000266 Ensembl Gene Model | MGI Sequence Detail 103117 C57BL/6J ±  kb
transcript ENSMUST00000112988 Ensembl | MGI Sequence Detail 2525 Not Applicable  
polypeptide ENSMUSP00000108612 Ensembl | MGI Sequence Detail 715 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 20
    Primer pair 4
    Other 1

    Microarray probesets 5
References
more
  • Summaries
    All 26
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:56619 Buchner G, et al., MID2, a homologue of the Opitz syndrome gene MID1: similarities in subcellular localization and differences in expression during development. Hum Mol Genet. 1999 Aug;8(8):1397-407
  • Latest
    J:244447 Li B, et al., Mid1/Mid2 expression in craniofacial development and a literature review of X-linked opitz syndrome. Mol Genet Genomic Med. 2016 Jan;4(1):95-105

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory