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Commd8 Gene Detail
Summary
  • Symbol
    Commd8
  • Name
    COMM domain containing 8
  • Synonyms
    D5Buc26e, IMAGE:1958590
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343485
    NCBI Gene: 27784
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:72156576-72168183 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 38.44 cM
  • Mapping Data
    3 experiments
  • Sequence Tag
Strain
Comparison
more
  • SNPs within 2kb
    69 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1343485
protein coding gene Chr5:72156575-72168189 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029610
protein coding gene Chr5:72060176-72071805 (-)
A/J MGP_AJ_G0029578
protein coding gene Chr5:69369474-69381081 (-)
AKR/J MGP_AKRJ_G0029526
protein coding gene Chr5:71576189-71587795 (-)
BALB/cJ MGP_BALBcJ_G0029587
protein coding gene Chr5:70036189-70047801 (-)
C3H/HeJ MGP_C3HHeJ_G0029310
protein coding gene Chr5:71948527-71960132 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030041
protein coding gene Chr5:75051551-75063167 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027281
protein coding gene Chr5:65097360-65109726 (-)
CAST/EiJ MGP_CASTEiJ_G0028718
protein coding gene Chr5:71072301-71083972 (-)
CBA/J MGP_CBAJ_G0029279
protein coding gene Chr5:77442247-77453859 (-)
DBA/2J MGP_DBA2J_G0029425
protein coding gene Chr5:69427750-69439354 (-)
FVB/NJ MGP_FVBNJ_G0029385
protein coding gene Chr5:68608072-68619680 (-)
LP/J MGP_LPJ_G0029510
protein coding gene Chr5:72545222-72556840 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029413
protein coding gene Chr5:80841786-80854437 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030074
protein coding gene Chr5:71174696-71186316 (-)
PWK/PhJ MGP_PWKPhJ_G0028442
protein coding gene Chr5:68389191-68401096 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028276
protein coding gene Chr5:70541320-70553352 (-)
WSB/EiJ MGP_WSBEiJ_G0028798
protein coding gene Chr5:71418562-71430342 (-)



Homology
more
  • Human Ortholog
    COMMD8, COMM domain containing 8
  • Vertebrate Orthologs
    10
  • Human Ortholog
    COMMD8, COMM domain containing 8
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 54951
    neXtProt AC: NX_Q9NX08
    UniProt: Q9NX08

  • Chr Location
    4p12; chr4:47450793-47463702 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9873
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: COMMD8
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Spontaneous
    1
  • Genomic Mutations
    4 involving Commd8
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 27784 NCBI Gene Model | MGI Sequence Detail 11608 C57BL/6J ±  kb
transcript NM_001356614 RefSeq | MGI Sequence Detail 4110 C57BL/6  
polypeptide Q9CZG3 UniProt | EBI | MGI Sequence Detail 183 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 94
    Genomic 8
    cDNA 85
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2141294
References
more
  • Summaries
    All 41
    Gene Ontology 2
    Phenotypes 17
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:125425 Howell GR, et al., Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations. Genetics. 2007 Feb;175(2):699-707

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory