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Ccl27a Gene Detail
Summary
  • Symbol
    Ccl27a
  • Name
    chemokine (C-C motif) ligand 27A
  • Synonyms
    ALP, Ccl27, CTACK, CTAK, ESkine, ESkine, ILC, mILC, PESKY, Scya27, Scya27a, skinskine
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343459
    NCBI Gene: 20301
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:41769467-41774200 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 22.08 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    16 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1343459
protein coding gene Chr4:41769467-41774247 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0028134
protein coding gene Chr4:38226465-38236990 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0028146
protein coding gene Chr4:38569208-38576748 (-)
C3H/HeJ MGP_C3HHeJ_G0027868
protein coding gene Chr4:39698993-39708669 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0027845
protein coding gene Chr4:42604240-42609019 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0027956
protein coding gene Chr4:37474237-37476317 (-)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0027048
protein coding gene Chr4:38195720-38210610 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CCL27, C-C motif chemokine ligand 27
  • Vertebrate Orthologs
    2
  • Human Ortholog
    CCL27, C-C motif chemokine ligand 27
    Orthology source: HGNC
  • Synonyms
    ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27
  • Links
    NCBI Gene ID: 10850
    neXtProt AC: NX_Q9Y4X3
    UniProt: Q9Y4X3

  • Chr Location
    9p13.3; chr9:34661883-34662692 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically and radiation induced
    1
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Ccl27a
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20301 NCBI Gene Model | MGI Sequence Detail 4734 C57BL/6J ±  kb
transcript NR_154591 RefSeq | MGI Sequence Detail 2853 C57BL/6  
polypeptide Q9Z1X0 UniProt | EBI | MGI Sequence Detail 120 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 7
Other
Accession IDs
less
MGI:1891388, MGI:2140607
References
more
  • Summaries
    All 39
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:27000 Forger JM 3rd, et al., Murine infection by vesicular stomatitis virus: initial characterization of the H-2d system. J Virol. 1991 Sep;65(9):4950-8
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory