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Ccl27a Gene Detail
Summary
  • Symbol
    Ccl27a
  • Name
    C-C motif chemokine ligand 27A
  • Synonyms
    ALP, Ccl27, CTACK, CTAK, ESkine, ESkine, ILC, mILC, PESKY, Scya27, Scya27a, skinskine
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343459
    NCBI Gene: 20301
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:41769467-41774247 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 22.08 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    16 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1343459
protein coding gene Chr4:41769467-41774251 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0028134
protein coding gene Chr4:38226465-38236990 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0028146
protein coding gene Chr4:38569208-38576748 (-)
C3H/HeJ MGP_C3HHeJ_G0027868
protein coding gene Chr4:39698993-39708669 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0027845
protein coding gene Chr4:42604240-42609019 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0027956
protein coding gene Chr4:37474237-37476317 (-)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0027048
protein coding gene Chr4:38195720-38210610 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CCL27, C-C motif chemokine ligand 27
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCL27, C-C motif chemokine ligand 27
  • Synonyms
    ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27
  • Links
    NCBI Gene ID: 10850
    neXtProt AC: NX_Q9Y4X3
    UniProt: Q9Y4X3

  • Chr Location
    9p13.3; chr9:34661880-34664048 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically and radiation induced
    1
  • Endonuclease-mediated
    2
  • Targeted
    2
  • Genomic Mutations
    1 involving Ccl27a
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073888 Ensembl Gene Model | MGI Sequence Detail 4781 C57BL/6J ±  kb
transcript ENSMUST00000108037 Ensembl | MGI Sequence Detail 590 Not Applicable  
polypeptide ENSMUSP00000103672 Ensembl | MGI Sequence Detail 164 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 7
Other
Accession IDs
less
MGI:1891388, MGI:2140607
References
more
  • Summaries
    All 44
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:27000 Forger JM 3rd, et al., Murine infection by vesicular stomatitis virus: initial characterization of the H-2d system. J Virol. 1991 Sep;65(9):4950-8
  • Latest
    J:330550 Davila ML, et al., CCL27 is a crucial regulator of immune homeostasis of the skin and mucosal tissues. iScience. 2022 Jun 17;25(6):104426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory