Drg1
Gene Detail

Symbol Name ID

Drg1 developmentally regulated GTP binding protein 1 MGI:1343297

Synonyms

Nedd3

Feature Type

protein coding gene

Genetic Map

Chromosome 11

2.23 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr11:3187360-3266415 bp, - strand From VEGA annotation of GRCm38   79056 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3060  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: GTP-binding protein DRG
Gene Tree: Drg1

Human homologs

Human Homolog		DRG1, developmentally regulated GTP binding protein 1
NCBI Gene ID		4733
neXtProt AC		NX_Q9Y295
Human Synonyms		NEDD3
Human Chr (Location)		22q12.2; chr22:31795539-31830172 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(34) : Gene trapped(34)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Component	cytoplasm, intermediate filament cytoskeleton, ...
Function	GTP binding, nucleotide binding

External Resources: FuncBase

Expression

Literature Summary: (6 records)
Data Summary: Results (189)    Tissues (108)    Images (34)
Theiler Stages: 17, 22, 23

Assay Type	Results
RNA in situ	189

cDNA source data(126)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(127) cDNA(126) Primer pair(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000000765 (Evidence)
Ensembl Gene Model	ENSMUSG00000020457 (Evidence)
Entrez Gene	13494 (Evidence)
UniGene	3250
DFCI	TC1572526, TC1692597, TC1729190
DoTS	DT.495323, DT.94137680, DT.97388022
NIA Mouse Gene Index	U032429
Consensus CDS Project	CCDS24355.1
International Mouse Knockout Project Status	Drg1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000000765	VEGA Gene Model | MGI Sequence Detail	79056	C57BL/6J
transcript	OTTMUST00000001481	VEGA | MGI Sequence Detail	1546	Not Applicable
polypeptide	OTTMUSP00000000703	VEGA | MGI Sequence Detail	367	Not Applicable

All sequences(64) RefSeq(2) UniProt(6)

Polymorphisms

SNPs(21 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR006074	GTP1/OBG, conserved site
InterPro	IPR006073	GTP binding domain
InterPro	IPR005225	Small GTP-binding protein domain
InterPro	IPR004095	TGS
InterPro	IPR012676	TGS-like
Protein Ontology	PR:000006688	developmentally-regulated GTP-binding protein 1

References

(Earliest) J:1344 Kumar S, et al., Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem Biophys Res Commun. 1992 Jun 30;185(3):1155-61
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(41)

Other accession IDs

MGD-MRK-12809, MGI:2143988, MGI:2144074, MGI:97296