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Drg1
Gene Detail
 Symbol
Name
ID
Drg1
developmentally regulated GTP binding protein 1
MGI:1343297
Synonyms Nedd3
Feature Type protein coding gene
Genetic Map
Chromosome 11
2.23 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:3187360-3266415 bp, - strand
From VEGA annotation of GRCm38

  79056 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3060  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: GTP-binding protein DRG
Gene Tree: Drg1

Human
homologs
Human Homolog DRG1, developmentally regulated GTP binding protein 1
NCBI Gene ID 4733
neXtProt AC  NX_Q9Y295
Human Synonyms  NEDD3
Human Chr (Location)  22q12.2; chr22:31399553-31434186 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(34) : Gene trapped(34)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Drg1 interacts with 88 markers (Mir18, Mir18b, Mir30a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Component cytoplasm, membrane, ...
Function GTP binding, identical protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (189)    Tissues (108)    Images (34)
Theiler Stages: 17, 22, 23
Assay TypeResults
RNA in situ 189
cDNA source data(126)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(127) cDNA(126) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000000765 (Evidence)
Ensembl Gene ModelENSMUSG00000020457 (Evidence)
Entrez Gene13494 (Evidence)
UniGene3250
DFCITC1572526, TC1692597, TC1729190
DoTSDT.495323, DT.94137680, DT.97388022
NIA Mouse Gene IndexU032429
Consensus CDS ProjectCCDS24355.1
International Mouse Knockout Project StatusDrg1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000765 VEGA Gene Model | MGI Sequence Detail 79056 C57BL/6J ±  kb
transcript OTTMUST00000001481 VEGA | MGI Sequence Detail 1546 Not Applicable 
polypeptide OTTMUSP00000000703 VEGA | MGI Sequence Detail 367 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(2) UniProt(6)
Polymorphisms SNPs within 2kb(262 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006074 GTP1/OBG, conserved site
InterPro IPR006073 GTP binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR005225 Small GTP-binding protein domain
InterPro IPR004095 TGS
InterPro IPR012676 TGS-like
Protein Ontology PR:000006688 developmentally-regulated GTP-binding protein 1
References (Earliest) J:1344 Kumar S, et al., Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem Biophys Res Commun. 1992 Jun 30;185(3):1155-61
(Latest) J:202495 Park CS, et al., Genome-wide analysis of H4K5 acetylation associated with fear memory in mice. BMC Genomics. 2013;14:539
All references(42)
Other
accession IDs
MGD-MRK-12809, MGI:2143988, MGI:2144074, MGI:97296

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory