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Ube2g2
Gene Detail
Symbol

Name
ID
Ube2g2
ubiquitin-conjugating enzyme E2G 2
MGI:1343188
Synonyms
1110003O05Rik, D10Xrf369, UBC7, Ubc7p
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:77622275-77645993 bp, + strand
From VEGA annotation of GRCm38

  23719 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6599  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: UBE2G2
Protein SuperFamily: ubiquitin-conjugating enzyme E2
Gene Tree: Ube2g2

Human
homologs
UBE2G2, ubiquitin-conjugating enzyme E2G 2
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 7327
neXtProt AC: NX_P60604

Human Synonyms: UBC7

Human Chr (Location): 21q22.3; chr21:44768580-44801836 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(1) Targeted(5)
Genomic Mutations involving Ube2g2 (3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Mutations Annotated to Human Diseases (1)   
Interactions
Ube2g2 interacts with 177 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process cellular protein catabolic process, ER-associated ubiquitin-dependent protein catabolic process, ...
Component cytoplasm, cytosol, ...
Function ATP binding, identical protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (252)    Tissues (132)    Images (16)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 236
RT-PCR 16
cDNA source data(102)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA UBE2G2 ; Xenbase ube2g2 ; ZFIN ube2g2    NEW 
Molecular
reagents
All nucleic(112) Genomic(9) cDNA(102) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000038229 (Evidence)
Ensembl Gene Model ENSMUSG00000009293 (Evidence)
Entrez Gene 22213 (Evidence)
UniGene 458125
DFCI TC1782005, TC1574318
DoTS DT.101402958, DT.534039, DT.110588250
EC 6.3.2.19
PDB 3FSH
Consensus CDS Project CCDS56722.1
International Mouse Phenotyping Consortium Status Ube2g2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000038229 VEGA Gene Model | MGI Sequence Detail 23719 C57BL/6J ±  kb
transcript OTTMUST00000098414 VEGA | MGI Sequence Detail 2031 Not Applicable 
polypeptide OTTMUSP00000055312 VEGA | MGI Sequence Detail 165 Not Applicable 

For the selected sequences
All sequences(55) RefSeq(2) UniProt(7)
Polymorphisms
SNPs within 2kb(114 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023313 Ubiquitin-conjugating enzyme, active site
InterPro IPR000608 Ubiquitin-conjugating enzyme, E2
InterPro IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Protein Ontology PR:000016975 ubiquitin-conjugating enzyme E2 G2
References
(Earliest) J:59327 Wiltshire T, et al., Perfect conserved linkage across the entire mouse chromosome 10 region homologous to human chromosome 21. Genome Res. 1999 Dec;9(12):1214-22
(Latest) J:211320 Liu W, et al., Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains. EMBO J. 2014 Jan 7;33(1):46-61
All references(42)
Other
accession IDs
MGD-MRK-36176, MGI:107602, MGI:1915721

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory