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Ube2g2
Gene Detail
 Symbol
Name
ID
Ube2g2
ubiquitin-conjugating enzyme E2G 2
MGI:1343188
Synonyms 1110003O05Rik, D10Xrf369, UBC7, Ubc7p
Feature Type protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:77622275-77645993 bp, + strand
From VEGA annotation of GRCm38

  23719 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6599  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: ubiquitin-conjugating enzyme E2
Gene Tree: Ube2g2

Human
homologs
Human Homolog UBE2G2, ubiquitin-conjugating enzyme E2G 2
NCBI Gene ID 7327
neXtProt AC  NX_P60604
Human Synonyms  UBC7
Human Chr (Location)  21q22.3; chr21:44768580-44801836 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(1) Targeted(5)
Genomic Mutations involving Ube2g2 (3)
Incidental mutations (data from Mutagenetix , APF )
Alleles Annotated to Human Diseases(1)   
Interactions
Ube2g2 interacts with 177 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process ER-associated ubiquitin-dependent protein catabolic process, protein K48-linked ubiquitination, ...
Component cytosol, endoplasmic reticulum
Function ATP binding, identical protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (252)    Tissues (132)    Images (16)
Theiler Stages: 13, 15, 17, 20, 22, 26, 28
Assay TypeResults
RNA in situ 236
RT-PCR 16
cDNA source data(102)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(112) Genomic(9) cDNA(102) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000038229 (Evidence)
Ensembl Gene ModelENSMUSG00000009293 (Evidence)
Entrez Gene22213 (Evidence)
UniGene458125
DFCITC1574318, TC1782005
DoTSDT.101402958, DT.110588250, DT.534039
EC6.3.2.19
PDB3FSH
Consensus CDS ProjectCCDS56722.1
International Mouse Knockout Project StatusUbe2g2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000038229 VEGA Gene Model | MGI Sequence Detail 23719 C57BL/6J ±  kb
transcript OTTMUST00000098414 VEGA | MGI Sequence Detail 2031 Not Applicable 
polypeptide OTTMUSP00000055312 VEGA | MGI Sequence Detail 165 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(2) UniProt(7)
Polymorphisms SNPs within 2kb(114 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023313 Ubiquitin-conjugating enzyme, active site
InterPro IPR000608 Ubiquitin-conjugating enzyme, E2
InterPro IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Protein Ontology PR:000016975 ubiquitin-conjugating enzyme E2 G2
References (Earliest) J:59327 Wiltshire T, et al., Perfect conserved linkage across the entire mouse chromosome 10 region homologous to human chromosome 21. Genome Res. 1999 Dec;9(12):1214-22
(Latest) J:211320 Liu W, et al., Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains. EMBO J. 2014 Jan 7;33(1):46-61
All references(42)
Other
accession IDs
MGD-MRK-36176, MGI:107602, MGI:1915721

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory