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Ube2g2 Gene Detail
Summary
  • Symbol
    Ube2g2
  • Name
    ubiquitin-conjugating enzyme E2G 2
  • Synonyms
    1110003O05Rik, D10Xrf369, UBC7, Ubc7p
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343188
    NCBI Gene: 22213
Location & Maps
more
  • Sequence Map
    Chr10:77622275-77645993 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23719 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    UBE2G2, ubiquitin conjugating enzyme E2G 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    UBE2G2, ubiquitin conjugating enzyme E2G 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    UBC7
  • Links
    NCBI Gene ID: 7327
    neXtProt AC: NX_P60604

  • Chr Location
    21q22.3; chr21:44768580-44801836 (-)  GRCh38.p2

Human Diseases
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  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    5
  • Genomic Mutations
    4 involving Ube2g2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000038229 VEGA Gene Model | MGI Sequence Detail 23719 C57BL/6J ±  kb
transcript OTTMUST00000098414 VEGA | MGI Sequence Detail 2031 Not Applicable  
polypeptide OTTMUSP00000055312 VEGA | MGI Sequence Detail 165 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    114 from dbSNP Build 137
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000016975 ubiquitin-conjugating enzyme E2 G2
  • PDB
  • EC
  • InterPro Domains
    IPR023313 Ubiquitin-conjugating enzyme, active site
    IPR000608 Ubiquitin-conjugating enzyme E2
    IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Molecular
Reagents
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  • All nucleic 112
    Genomic 9
    cDNA 102
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-36176, MGI:107602, MGI:1915721
References
more
  • Summaries
    All 40
    Developmental Gene Expression 4
    Diseases 2
    Gene Ontology 9
    Phenotypes 17
  • Earliest
    J:59327 Wiltshire T, et al., Perfect conserved linkage across the entire mouse chromosome 10 region homologous to human chromosome 21. Genome Res. 1999 Dec;9(12):1214-22
  • Latest
    J:211320 Liu W, et al., Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains. EMBO J. 2014 Jan 7;33(1):46-61

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory