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Calcoco2 Gene Detail
Summary
  • Symbol
    Calcoco2
  • Name
    calcium binding and coiled-coil domain 2
  • Synonyms
    2410154J16Rik, Ndp52, Ndp52l1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343177
    NCBI Gene: 76815
  • Gene Overview
    MyGene.info: CALCOCO2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:96099326-96111964 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 59.40 cM, cytoband C
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1343177
protein coding gene Chr11:96098916-96124624 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018998
protein coding gene Chr11:98390268-98403094 (-)
A/J MGP_AJ_G0018966
protein coding gene Chr11:94377953-94390725 (-)
AKR/J MGP_AKRJ_G0018936
protein coding gene Chr11:97288265-97301202 (-)
BALB/cJ MGP_BALBcJ_G0018939
protein coding gene Chr11:94863454-94877710 (-)
C3H/HeJ MGP_C3HHeJ_G0018753
protein coding gene Chr11:97431636-97444196 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019391
protein coding gene Chr11:101459716-101475480 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017021
protein coding gene Chr11:91866151-91885273 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0018724
protein coding gene Chr11:105614497-105627122 (-)
DBA/2J MGP_DBA2J_G0018832
protein coding gene Chr11:93949377-93963015 (-)
FVB/NJ MGP_FVBNJ_G0018821
protein coding gene Chr11:93424203-93437234 (-)
LP/J MGP_LPJ_G0018902
protein coding gene Chr11:98930717-98945750 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018848
protein coding gene Chr11:105605366-105619320 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019431
protein coding gene Chr11:97591797-97607421 (-)
PWK/PhJ MGP_PWKPhJ_G0018078
protein coding gene Chr11:94901529-94914114 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017867
protein coding gene Chr11:97305196-97324073 (-)
WSB/EiJ MGP_WSBEiJ_G0018356
protein coding gene Chr11:97488753-97500976 (-)



Homology
more
  • Human Ortholog
    CALCOCO2, calcium binding and coiled-coil domain 2
  • Human Ortholog
    CALCOCO2, calcium binding and coiled-coil domain 2
    Orthology source: HGNC
  • Synonyms
    NDP52
  • Links
    NCBI Gene ID: 10241
    neXtProt AC: NX_Q13137
    UniProt: Q13137

  • Chr Location
    17q21.32; chr17:48830988-48865245 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000006056 Ensembl Gene Model | MGI Sequence Detail 12639 C57BL/6J ±  kb
transcript ENSMUST00000068686 Ensembl | MGI Sequence Detail 1621 Not Applicable  
polypeptide ENSMUSP00000087407 Ensembl | MGI Sequence Detail 331 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR012852 Calcium binding and coiled-coil domain-like
Molecular
Reagents
less
  • All nucleic 22
    Genomic 8
    cDNA 14

    Microarray probesets 3
Other
Accession IDs
less
MGI:1924065, MGI:2144626
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 13
  • Earliest
    J:51104 Mohlke KL, et al., Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level. Genomics. 1998 Nov 15;54(1):19-30
  • Latest
    J:220278 Kim S, et al., NDP52 associates with phosphorylated tau in brains of an Alzheimer disease mouse model. Biochem Biophys Res Commun. 2014 Nov 7;454(1):196-201

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory