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Timm17b Gene Detail
Summary
  • Symbol
    Timm17b
  • Name
    translocase of inner mitochondrial membrane 17b
  • Synonyms
    17kDa, mTim17b, Sfc3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343176
    NCBI Gene: 21855
Location & Maps
more
  • Genetic Map
    Chromosome X, 3.56 cM
  • Mapping Data
    2 experiments
Homology
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  • Human Ortholog
    TIMM17B, translocase of inner mitochondrial membrane 17 homolog B (yeast)
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TIMM17B, translocase of inner mitochondrial membrane 17 homolog B (yeast)
    Orthology source: HomoloGene
  • Synonyms
    DXS9822, JM3, TIM17B
  • Links
    NCBI Gene ID: 10245
    neXtProt AC: NX_O60830

  • Chr Location
    Xp11.23; chrX:48893447-48898143 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    3
  • Gene trapped
    1
  • Targeted
    2
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018003 VEGA Gene Model | MGI Sequence Detail 8995 C57BL/6J ±  kb
transcript OTTMUST00000043484 VEGA | MGI Sequence Detail 2381 Not Applicable  
polypeptide OTTMUSP00000019542 VEGA | MGI Sequence Detail 172 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    63 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000016345 mitochondrial import inner membrane translocase subunit Tim17-B
  • InterPro Domains
    IPR005678 Mitochondrial inner membrane translocase complex, subunit Tim17
    IPR003397 Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24
Molecular
Reagents
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  • All nucleic 73
    Genomic 2
    cDNA 71

    Microarray probesets 4
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:55629 Bauer MF, et al., Genetic and structural characterization of the human mitochondrial inner membrane translocase. J Mol Biol. 1999 May 28;289(1):69-82
  • Latest
    J:226997 Bebee TW, et al., The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. Elife. 2015;4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory