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Snf8 Gene Detail
Summary
  • Symbol
    Snf8
  • Name
    SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
  • Synonyms
    D11Moh34, MGC:7335
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343161
    NCBI Gene: 27681
  • Gene Overview
    MyGene.info: SNF8
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr11:96034885-96047430 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12546 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 59.24 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SNF8, SNF8, ESCRT-II complex subunit
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SNF8, SNF8, ESCRT-II complex subunit
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Dot3, EAP30, VPS22
  • Links
    NCBI Gene ID: 11267
    neXtProt AC: NX_Q96H20
    UniProt: Q96H20

  • Chr Location
    17q21.32; chr17:48930096-48944842 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000001957 VEGA Gene Model | MGI Sequence Detail 12546 C57BL/6J ±  kb
    transcript OTTMUST00000003921 VEGA | MGI Sequence Detail 1004 Not Applicable  
    polypeptide OTTMUSP00000001898 VEGA | MGI Sequence Detail 258 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      127 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 104
      Genomic 12
      cDNA 92

      Microarray probesets 4
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 15
    • Earliest
      J:51104 Mohlke KL, et al., Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level. Genomics. 1998 Nov 15;54(1):19-30
    • Latest
      J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory