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Ube2z Gene Detail
Summary
  • Symbol
    Ube2z
  • Name
    ubiquitin-conjugating enzyme E2Z
  • Synonyms
    C030047H17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343160
    NCBI Gene: 268470
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:96047431-96065364 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 59.28 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    105 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1343160
protein coding gene Chr11:96047431-96065388 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018996
protein coding gene Chr11:98322527-98342361 (-)
A/J MGP_AJ_G0018964
protein coding gene Chr11:94327257-94344794 (-)
AKR/J MGP_AKRJ_G0018934
protein coding gene Chr11:97232669-97252036 (-)
BALB/cJ MGP_BALBcJ_G0018937
protein coding gene Chr11:94809966-94828504 (-)
C3H/HeJ MGP_C3HHeJ_G0018751
protein coding gene Chr11:97372984-97391576 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019389
protein coding gene Chr11:101399355-101417303 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017019
protein coding gene Chr11:91812844-91832624 (-)
CAST/EiJ MGP_CASTEiJ_G0018305
protein coding gene Chr11:98187646-98206474 (-)
CBA/J MGP_CBAJ_G0018722
protein coding gene Chr11:105545037-105565709 (-)
DBA/2J MGP_DBA2J_G0018830
protein coding gene Chr11:93896917-93915076 (-)
FVB/NJ MGP_FVBNJ_G0018819
protein coding gene Chr11:93372391-93390359 (-)
LP/J MGP_LPJ_G0018900
protein coding gene Chr11:98876172-98894587 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018846
protein coding gene Chr11:105547050-105568769 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019429
protein coding gene Chr11:97532377-97551236 (-)
PWK/PhJ MGP_PWKPhJ_G0018076
protein coding gene Chr11:94839901-94859131 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017865
protein coding gene Chr11:97241092-97259516 (-)
WSB/EiJ MGP_WSBEiJ_G0018354
protein coding gene Chr11:97432709-97450283 (-)



Homology
more
  • Human Ortholog
    UBE2Z, ubiquitin conjugating enzyme E2 Z
  • Vertebrate Orthologs
    8
  • Human Ortholog
    UBE2Z, ubiquitin conjugating enzyme E2 Z
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HOYS7, USE1
  • Links
    NCBI Gene ID: 65264
    neXtProt AC: NX_Q9H832
    UniProt: Q9H832

  • Chr Location
    17q21.32; chr17:48908369-48929060 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 268470 NCBI Gene Model | MGI Sequence Detail 17934 C57BL/6J ±  kb
transcript NM_172300 RefSeq | MGI Sequence Detail 3974 C57BL/6  
polypeptide Q3UE37 UniProt | EBI | MGI Sequence Detail 356 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 175
    Genomic 12
    cDNA 163

    Microarray probesets 6
Other
Accession IDs
less
MGI:2144484, MGI:2441876
References
more
  • Summaries
    All 34
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:51104 Mohlke KL, et al., Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level. Genomics. 1998 Nov 15;54(1):19-30
  • Latest
    J:198126 Lee PC, et al., Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system. Mol Cell. 2013 Apr 25;50(2):172-84

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/27/2018
MGI 6.13
The Jackson Laboratory