About   Help   FAQ
Ube2z
Gene Detail
Symbol

Name
ID
Ube2z
ubiquitin-conjugating enzyme E2Z (putative)
MGI:1343160
Synonyms
C030047H17Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
59.28 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:96047432-96065388 bp, - strand
From VEGA annotation of GRCm38

  17957 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11319  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ube2z

Human
homologs
Human Homolog UBE2Z, ubiquitin-conjugating enzyme E2Z
NCBI Gene ID 65264
neXtProt AC  NX_Q9H832
Human Synonyms  USE1
Human Chr (Location)  17q21.32; chr17:48908369-48929060 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Genomic Mutations involving Ube2z (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ube2z interacts with 374 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process apoptotic process, protein polyubiquitination, ...
Component cytoplasm, nucleoplasm, ...
Function ATP binding, ligase activity, ...
External Resources: FuncBase
Expression
cDNA source data(162)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(174) Genomic(12) cDNA(162)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000001958 (Evidence)
Ensembl Gene ModelENSMUSG00000014349 (Evidence)
Entrez Gene268470 (Evidence)
UniGene38802
DFCITC1666938, TC1572865, TC1656764, TC1613962, TC1602299
DoTSDT.40172170, DT.110504799, DT.101378596, DT.101303642, DT.91301615, DT.534292
NIA Mouse Gene IndexU033315
EC6.3.2.19
Consensus CDS ProjectCCDS36289.1
International Mouse Knockout Project StatusUbe2z
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001958 VEGA Gene Model | MGI Sequence Detail 17957 C57BL/6J ±  kb
transcript OTTMUST00000003927 VEGA | MGI Sequence Detail 3997 Not Applicable 
polypeptide OTTMUSP00000001900 VEGA | MGI Sequence Detail 356 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(105 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000608 Ubiquitin-conjugating enzyme, E2
InterPro IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Protein Ontology PR:000016991 ubiquitin-conjugating enzyme E2 Z
References
(Earliest) J:51104 Mohlke KL, et al., Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level. Genomics. 1998 Nov 15;54(1):19-30
(Latest) J:198126 Lee PC, et al., Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system. Mol Cell. 2013 Apr 25;50(2):172-84
All references(32)
Other
accession IDs
MGI:2144484, MGI:2441876

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory