About   Help   FAQ
Ikzf4 Gene Detail
Summary
  • Symbol
    Ikzf4
  • Name
    IKAROS family zinc finger 4
  • Synonyms
    A630026H08Rik, Eos, Zfpn1a4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343139
    NCBI Gene: 22781
  • Gene Overview
    MyGene.info: IKZF4
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:128630843-128645991 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 77.11 cM, cytoband D3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    316 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1343139
protein coding gene Chr10:128630839-128669809 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017875
protein coding gene Chr10:132391084-132406152 (-)
A/J MGP_AJ_G0017850
protein coding gene Chr10:127079082-127094173 (-)
AKR/J MGP_AKRJ_G0017813
protein coding gene Chr10:130795122-130810035 (-)
BALB/cJ MGP_BALBcJ_G0017814
protein coding gene Chr10:127445873-127461309 (-)
C3H/HeJ MGP_C3HHeJ_G0017637
protein coding gene Chr10:130960979-130976101 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018269
protein coding gene Chr10:136868477-136883530 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015947
protein coding gene Chr10:120994927-121010071 (-)
CAST/EiJ MGP_CASTEiJ_G0017198
protein coding gene Chr10:131681671-131698599 (-)
CBA/J MGP_CBAJ_G0017607
protein coding gene Chr10:142447264-142462367 (-)
DBA/2J MGP_DBA2J_G0017713
protein coding gene Chr10:126140451-126155538 (-)
FVB/NJ MGP_FVBNJ_G0017708
protein coding gene Chr10:125053711-125070002 (-)
LP/J MGP_LPJ_G0017787
protein coding gene Chr10:132987542-133003128 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017736
protein coding gene Chr10:145019766-145035821 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018309
protein coding gene Chr10:130896517-130911641 (-)
PWK/PhJ MGP_PWKPhJ_G0016983
protein coding gene Chr10:126393818-126410042 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016772
protein coding gene Chr10:130011525-130026976 (-)
WSB/EiJ MGP_WSBEiJ_G0017257
protein coding gene Chr10:131116969-131133148 (-)



Homology
more
  • Human Ortholog
    IKZF4, IKAROS family zinc finger 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    IKZF4, IKAROS family zinc finger 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    EOS, ZNFN1A4
  • Links
    NCBI Gene ID: 64375
    neXtProt AC: NX_Q9H2S9
    UniProt: Q9H2S9

  • Chr Location
    12q13.2; chr12:56007647-56038435 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002578 Ensembl Gene Model | MGI Sequence Detail 15149 C57BL/6J ±  kb
transcript ENSMUST00000221150 Ensembl | MGI Sequence Detail 2213 Not Applicable  
polypeptide ENSMUSP00000152617 Ensembl | MGI Sequence Detail 686 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    cDNA 29
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2441811
References
more
  • Summaries
    All 47
    Developmental Gene Expression 8
    Gene Ontology 8
    Phenotypes 4
  • Earliest
    J:53896 Honma Y, et al., Eos: a novel member of the Ikaros gene family expressed predominantly in the developing nervous system. FEBS Lett. 1999 Mar 19;447(1):76-80
  • Latest
    J:259241 Yang HY, et al., MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription Factor. Immunity. 2016 Jul 19;45(1):83-93

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/11/2018
MGI 6.13
The Jackson Laboratory