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Ndufa2
Gene Detail
Symbol

Name
ID
Ndufa2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
MGI:1343103
Synonyms
B8, C1-B8
Feature Type
protein coding gene
Genetic Map
Chromosome 18
19.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:36742332-36744557 bp, - strand
From VEGA annotation of GRCm38

  2226 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37628  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NDUFA2
Protein SuperFamily: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2
Gene Tree: Ndufa2

Human
homologs
NDUFA2, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 4695
neXtProt AC: NX_O43678

Human Synonyms: B8, CD14, CIB8

Human Chr (Location): 5q31.2; chr5:140645363-140647785 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NDUFA2

Mutations,
alleles, and
phenotypes
All mutations/alleles(29) : Gene trapped(27) Targeted(2)
Incidental mutations (data from APF , CvDC )
Interactions
Ndufa2 interacts with 20 markers (Mir149, Mir194-1, Mir194-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process oxidation-reduction process, transport
Component membrane, mitochondrial inner membrane, ...
Function NADH dehydrogenase (ubiquinone) activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (105)    Tissues (100)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
Northern blot 1
RT-PCR 10
cDNA source data(177)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ndufa2 ; ZFIN ndufa2    NEW 
Molecular
reagents
All nucleic(180) cDNA(178) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000042397 (Evidence)
Ensembl Gene Model ENSMUSG00000014294 (Evidence)
Entrez Gene 17991 (Evidence)
UniGene 29867
DFCI TC1572666
DoTS DT.99869073, DT.495740
NIA Mouse Gene Index U038343
Consensus CDS Project CCDS29161.1
International Mouse Phenotyping Consortium Status Ndufa2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042397 VEGA Gene Model | MGI Sequence Detail 2226 C57BL/6J ±  kb
transcript OTTMUST00000111747 VEGA | MGI Sequence Detail 572 Not Applicable 
polypeptide OTTMUSP00000062625 VEGA | MGI Sequence Detail 99 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(49 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016464 NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2
InterPro IPR007741 Ribosomal protein/NADH dehydrogenase domain
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000011072 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
References
(Earliest) J:54917 Murdock DG, et al., Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart/muscle isoform of the adenine nucleotide translocator. J Biol Chem. 1999 May 14;274(20):14429-33
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGI:2147331

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory