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Ndufa2
Gene Detail
 Symbol
Name
ID
Ndufa2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
MGI:1343103
Synonyms B8, C1-B8
Feature Type protein coding gene
Genetic Map
Chromosome 18
19.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:36742332-36744557 bp, - strand
From VEGA annotation of GRCm38

  2226 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37628  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2
Gene Tree: Ndufa2

Human
homologs
Human Homolog NDUFA2, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NCBI Gene ID 4695
neXtProt AC  NX_O43678
Human Synonyms  B8, CD14, CIB8
Human Chr (Location)  5q31.2; chr5:140645363-140647785 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human NDUFA2
Mutations,
alleles, and
phenotypes
All mutations/alleles(29) : Gene trapped(27) Targeted(2)
Incidental mutations (data from APF )
Interactions
Ndufa2 interacts with 20 markers (Mir149, Mir194-1, Mir194-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process oxidation-reduction process, transport
Component membrane, mitochondrial inner membrane, ...
Function NADH dehydrogenase (ubiquinone) activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (105)    Tissues (100)    Images (15)
Theiler Stages: 1, 2, 3, 5, 22, 28
Assay TypeResults
RNA in situ 94
Northern blot 1
RT-PCR 10
cDNA source data(177)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(180) cDNA(178) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000042397 (Evidence)
Ensembl Gene ModelENSMUSG00000014294 (Evidence)
Entrez Gene17991 (Evidence)
UniGene29867
DFCITC1572666
DoTSDT.495740, DT.99869073
NIA Mouse Gene IndexU038343
Consensus CDS ProjectCCDS29161.1
International Mouse Knockout Project StatusNdufa2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042397 VEGA Gene Model | MGI Sequence Detail 2226 C57BL/6J ±  kb
transcript OTTMUST00000111747 VEGA | MGI Sequence Detail 572 Not Applicable 
polypeptide OTTMUSP00000062625 VEGA | MGI Sequence Detail 99 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(49 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016464 NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2
InterPro IPR007741 Ribosomal protein/NADH dehydrogenase domain
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000011072 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
References (Earliest) J:54917 Murdock DG, et al., Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart/muscle isoform of the adenine nucleotide translocator. J Biol Chem. 1999 May 14;274(20):14429-33
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)
Other
accession IDs
MGI:2147331

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory