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Cstf2
Gene Detail
 Symbol
Name
ID
Cstf2
cleavage stimulation factor, 3' pre-RNA subunit 2
MGI:1343054
Synonyms C630034J23Rik, Cstf64
Feature Type protein coding gene
Genetic Map
Chromosome X
55.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:134059187-134086819 bp, + strand
From VEGA annotation of GRCm38

  27633 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:80171  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Cstf2

Human
homologs
Human Homolog CSTF2, cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
NCBI Gene ID 1478
neXtProt AC  NX_P33240
Human Synonyms  CstF-64
Human Chr (Location)  Xq22.1; chrX:100820359-100840935 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(6) Targeted(2)
Incidental mutations (data from APF )
Interactions
Cstf2 interacts with 309 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process mRNA processing
Component cleavage body, mRNA cleavage and polyadenylation specificity factor complex, ...
Function nucleic acid binding, nucleotide binding, ...
External Resources: FuncBase
Expression
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000019011 (Evidence)
Ensembl Gene ModelENSMUSG00000031256 (Evidence)
Entrez Gene108062 (Evidence)
NIA Mouse Gene IndexU020190
Consensus CDS ProjectCCDS30389.1, CCDS72430.1
International Mouse Knockout Project StatusCstf2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019011 VEGA Gene Model | MGI Sequence Detail 27633 C57BL/6J ±  kb
transcript OTTMUST00000045619 VEGA | MGI Sequence Detail 4502 Not Applicable 
polypeptide OTTMUSP00000020509 VEGA | MGI Sequence Detail 580 Not Applicable 

For the selected sequences
All sequences(72) RefSeq(15) UniProt(7)
Polymorphisms RFLP(1) : SNPs within 2kb(89 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025742 Cleavage stimulation factor subunit 2, hinge domain
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
InterPro IPR026896 Transcription termination and cleavage factor C-terminal domain
Protein Ontology PR:000005976 cleavage stimulation factor 64 kDa subunit
References (Earliest) J:36814 Takagaki Y, et al., The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation. Cell. 1996 Nov 29;87(5):941-52
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)
Other
accession IDs
MGI:2442983

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory