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Actl7b Gene Detail
Summary
  • Symbol
    Actl7b
  • Name
    actin-like 7b
  • Synonyms
    ENSMUSG00000070980, Tact1, t-actin 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343053
    NCBI Gene: 11471
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:56740005-56741425 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 31.66 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1343053
protein coding gene Chr4:56740005-56741443 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028307
protein coding gene Chr4:55499977-55501415 (-)
A/J MGP_AJ_G0028268
protein coding gene Chr4:53379749-53381187 (-)
AKR/J MGP_AKRJ_G0028217
protein coding gene Chr4:54851949-54853387 (-)
BALB/cJ MGP_BALBcJ_G0028287
protein coding gene Chr4:53535943-53537381 (-)
C3H/HeJ MGP_C3HHeJ_G0028008
protein coding gene Chr4:55362121-55363559 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028728
protein coding gene Chr4:57478512-57479950 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026036
protein coding gene Chr4:50183494-50187514 (-)
CAST/EiJ MGP_CASTEiJ_G0027446
protein coding gene Chr4:55066266-55067704 (-)
CBA/J MGP_CBAJ_G0027973
protein coding gene Chr4:59462960-59464398 (-)
DBA/2J MGP_DBA2J_G0028123
protein coding gene Chr4:53287374-53288812 (-)
FVB/NJ MGP_FVBNJ_G0028090
protein coding gene Chr4:52497343-52498781 (-)
LP/J MGP_LPJ_G0028222
protein coding gene Chr4:55601314-55602752 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028114
protein coding gene Chr4:62630047-62631485 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028764
protein coding gene Chr4:55031626-55033064 (-)
PWK/PhJ MGP_PWKPhJ_G0027171
protein coding gene Chr4:53267550-53268988 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026999
protein coding gene Chr4:54311994-54313432 (-)
WSB/EiJ MGP_WSBEiJ_G0027524
protein coding gene Chr4:54983728-54985166 (-)



Homology
more
  • Human Ortholog
    ACTL7B, actin like 7B
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ACTL7B, actin like 7B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    Tact1
  • Links
    NCBI Gene ID: 10880
    neXtProt AC: NX_Q9Y614
    UniProt: Q9Y614

  • Chr Location
    9q31.3; chr9:108854588-108855995 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 11471 NCBI Gene Model | MGI Sequence Detail 1421 C57BL/6J ±  kb
transcript NM_025271 RefSeq | MGI Sequence Detail 1424 Not Specified  
polypeptide Q9QY83 UniProt | EBI | MGI Sequence Detail 418 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:3704232
References
more
  • Summaries
    All 25
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:56030 Chadwick BP, et al., Cloning, mapping, and expression of two novel actin genes, actin-like-7A (ACTL7A) and actin-like-7B (ACTL7B), from the familial dysautonomia candidate region on 9q31. Genomics. 1999 Jun 15;58(3):302-9
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory